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Spexin acetate(1370290-58-6 free base)

🥰Excellent
Catalog No. TP1930L1

Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Attenuates LH secretion in goldfish. Exhibits anxiolytic effects in vivo.

Spexin acetate(1370290-58-6 free base)
Other Forms of Spexin acetate(1370290-58-6 free base):

Spexin acetate(1370290-58-6 free base)

🥰Excellent
Purity: 95.43%
Catalog No. TP1930L1
Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Attenuates LH secretion in goldfish. Exhibits anxiolytic effects in vivo.
Pack SizePriceAvailabilityQuantity
1 mg$116In Stock
5 mg$268In Stock
10 mg$395In Stock
25 mg$592In Stock
50 mg$828In Stock
100 mg$1,130In Stock
200 mg$1,520In Stock
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Purity:95.43%
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Product Introduction

Bioactivity
Description
Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Attenuates LH secretion in goldfish. Exhibits anxiolytic effects in vivo.
Chemical Properties
Molecular Weight1680.94
FormulaC76H117N19O22S
SmilesCC(O)=O.O=C(O)CC[C@@H](C(N)=O)NC([C@H](C)NC(CNC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CC(C)C)NC([C@H](CCSC)NC([C@H](C)NC([C@H](CCC(N)=O)NC([C@H]2N(C([C@H]([C@H](O)C)NC([C@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CC(N)=O)N)=O)=O)=O)CCC2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Relative Density.no data available
SequenceH-Asn-Trp-Thr-Pro-Gln-Ala-Met-Leu-Tyr-Leu-Lys-Gly-Ala-Glu-NH2
Sequence ShortNWTPQAMLYLKGAE
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

Spexin acetate(1370290-58-6 free base)Spexin acetate(1370290586 free base)Spexin acetate(1370290 58 6 free base)NeuropeptideYReceptorNeuropeptide Y ReceptorGalanin receptor
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