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BCMA/TNFRSF17 Protein, Human, Recombinant

(Synonyms: Tumor necrosis factor receptor superfamily member 17, TNFRSF17, CD_antigen: CD269, BCM, B-cell maturation protein) Copy Product Info

Synonyms: Tumor necrosis factor receptor superfamily member 17, TNFRSF17, CD_antigen: CD269, BCM, B-cell maturation protein

Catalog No. TMPS-00150 Copy Product Info
BCMA/TNFRSF17 Protein, Human, Recombinant is expressed in E. coli. The accession number is Q02223.
BCMA/TNFRSF17 Protein, Human, Recombinant
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Pack SizePriceUSA StockGlobal StockQuantity
5 µg$1287-10 days7-10 days
10 µg$2137-10 days7-10 days
20 µg$3567-10 days7-10 days
50 µg$7357-10 days7-10 days
100 µg$1,2707-10 days7-10 days
200 µg$2,2207-10 days7-10 days
500 µg$4,6507-10 days7-10 days
1 mg$8,1307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Fully biologically active when compared to standard. The ED 50 as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less than 40.0 ng/ml, corresponding to a specific activity of > 2.5 × 10 4 IU/mg in the presence of 100.0 ng/ml human APRIL.
Description
BCMA/TNFRSF17 Protein, Human, Recombinant is expressed in E. coli. The accession number is Q02223.
Species
Human
Expression System
E. coli
TagTag Free
Accession NumberQ02223
ConstructionAla5-Ala54
Protein Purity
> 98% as determined by SDS-PAGE; > 98% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a 0.2 μm filtered solution in 30% acetonitrile, 0.1% TFA.
ReconstitutionIt is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
SynonymsTumor necrosis factor receptor superfamily member 17, TNFRSF17, CD_antigen: CD269, BCM, B-cell maturation protein
Research Background
BCMA, a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines and plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107 amino acid extracellular domain.
Chemical Properties
Molecular Weight5.4 kDa (Predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageUpon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.

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Related Tags: BCMA/TNFRSF17 Protein, Human, Recombinant chemical structure | BCMA/TNFRSF17 Protein, Human, Recombinant molecular weight