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Anti-Integrin alpha V beta 6 Antibody (1A563) is a Mouse antibody targeting Integrin alpha V beta 6. Anti-Integrin alpha V beta 6 Antibody (1A563) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
| Description | Anti-Integrin alpha V beta 6 Antibody (1A563) is a Mouse antibody targeting Integrin alpha V beta 6. Anti-Integrin alpha V beta 6 Antibody (1A563) can be used in ELISA. |
| Synonyms | ITGAV & ITGB6, integrin, α5 (fibronectin receptor, α polypeptide), integrin, alpha 5 (fibronectin receptor, alpha polypeptide), Integrin α V β 6, Integrin alpha V β6 |
| Ig Type | Mouse IgG1 |
| Clone | 1A563 |
| Reactivity | Human |
| Specificity | Human Integrin alpha V beta 6 |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Human ITGAV & ITGB6 Heterodimer (rh Human ITGAV & ITGB6 Heterodimer; TMPY-03878; P06756-1 & P18564-1; Met1-Val992 & Met1-Asn707). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of ITGAV&ITGB6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Human ITGAV & ITGB6 Heterodimer Protein (TMPY-03878) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |

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