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Anti-Integrin alpha V beta 6 Antibody (1A563)

🥰Excellent
Catalog No. TMAY-03936

Anti-Integrin alpha V beta 6 Antibody (1A563) is a Mouse antibody targeting Integrin alpha V beta 6. Anti-Integrin alpha V beta 6 Antibody (1A563) can be used in ELISA.

Anti-Integrin alpha V beta 6 Antibody (1A563)

Anti-Integrin alpha V beta 6 Antibody (1A563)

🥰Excellent
Catalog No. TMAY-03936
Anti-Integrin alpha V beta 6 Antibody (1A563) is a Mouse antibody targeting Integrin alpha V beta 6. Anti-Integrin alpha V beta 6 Antibody (1A563) can be used in ELISA.
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Product Introduction

Bioactivity
Description
Anti-Integrin alpha V beta 6 Antibody (1A563) is a Mouse antibody targeting Integrin alpha V beta 6. Anti-Integrin alpha V beta 6 Antibody (1A563) can be used in ELISA.
Ig Type
Monoclonal Mouse IgG1
Clone
1A563
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Human ITGAV & ITGB6 Heterodimer (rh Human ITGAV & ITGB6 Heterodimer; TMPY-03878; P06756-1 & P18564-1; Met1-Val992 & Met1-Asn707). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundIntegrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of ITGAV&ITGB6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Human ITGAV & ITGB6 Heterodimer Protein (TMPY-03878)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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