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Anti-Integrin alpha V beta 6 Antibody (1A563) is a Mouse antibody targeting Integrin alpha V beta 6. Anti-Integrin alpha V beta 6 Antibody (1A563) can be used in ELISA.
Description | Anti-Integrin alpha V beta 6 Antibody (1A563) is a Mouse antibody targeting Integrin alpha V beta 6. Anti-Integrin alpha V beta 6 Antibody (1A563) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 1A563 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Human ITGAV & ITGB6 Heterodimer (rh Human ITGAV & ITGB6 Heterodimer; TMPY-03878; P06756-1 & P18564-1; Met1-Val992 & Met1-Asn707). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of ITGAV&ITGB6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human Human ITGAV & ITGB6 Heterodimer Protein (TMPY-03878) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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