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Anti-gp130/IL6ST Antibody-APC (7J799)
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Catalog No. TMAY-03136A
Alias interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130
Anti-gp130/IL6ST Antibody-APC (7J799) is a APC-conjugated Rabbit antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody-APC (7J799) can be used in FCM.
Anti-gp130/IL6ST Antibody-APC (7J799)
Anti-gp130/IL6ST Antibody-APC (7J799)
😃Good
Catalog No. TMAY-03136AAlias interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130
Anti-gp130/IL6ST Antibody-APC (7J799) is a APC-conjugated Rabbit antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody-APC (7J799) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $81 | 7-10 days | |
| 100 T | $258 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: FCM Reactivity: Mouse |
| Alias | interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130 |
| Ig Type | Rabbit IgG |
| Clone | 7J799 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of Mouse IL6ST(CD130) expression on BABL/c splenocytes. Cells were stained with APC-conjugated anti-Mouse IL6ST(CD130). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL6ST/gp130/CD130 (rM IL6ST/gp130/CD130; TMPY-01832; NP_034690.3; Met1-Glu617) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all cytokine receptors. CD130/gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and Oncostatin M (OSM). CD130/gp130 functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. CD130/gp130 plays a critical role in regulating myocyte apoptosis. Alternatively, spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1, and BSF3 can utilize gp130 for initiating signal transmission. CD130/gp130 binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. CD130/gp130 may have a role in embryonic development. The type I OSM receptor is capable of transducing OSM-specific signaling events. |
| Conjucates | APC |
| Others Formats | Unconjugated/PE |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Protein: Mouse IL6ST/gp130/CD130 Protein (TMPY-01832) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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