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Antioxidant peptide A acetate

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Catalog No. TP1869L
Alias Antioxidant peptide A acetate (159147-88-3 free base)

Antioxidant peptide A acetate is a short peptide, which contains alternative aromatic or sulfur-containing amino acid.

Antioxidant peptide A acetate

Antioxidant peptide A acetate

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🥰Excellent
Purity: 99.4%
Catalog No. TP1869LAlias Antioxidant peptide A acetate (159147-88-3 free base)
Antioxidant peptide A acetate is a short peptide, which contains alternative aromatic or sulfur-containing amino acid.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$52In StockIn Stock
5 mg$153In StockIn Stock
10 mg$248In StockIn Stock
25 mg$413In StockIn Stock
50 mg$587In StockIn Stock
100 mg$792In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.4%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Antioxidant peptide A acetate is a short peptide, which contains alternative aromatic or sulfur-containing amino acid.
In vitro
The effects of 10-100 μM of Antioxidant peptide A (Pep-A) concentrations are studied on the superoxide dismutase (SOD) enzyme activity. The enzyme activity decreases by 0.5 and 0.7-folds at 10 and 50 μM Antioxidant peptide A concentrations, respectively, and increases by 1.79-folds at 100 μM Antioxidant peptide A treatment, indicating that this concentration can be ideal for the treatment on Y79 a, RB cells. Furthermore, the Antioxidant peptide A can be involved in decreasing the ROS by increasing the antioxidant enzyme activity. A similar increase in the antioxidative enzyme levels in the presence of Hoki skin antioxidative peptide in hepatocarcinoma cells is attributed to the peptide’s role in maintaining the redox balance in the cellular environment. Cell viability analysis results show that the Antioxidant peptide A shows no toxicity to cancerous (Y79) cells and non-cancerous cells even after 48 h of treatment. The Y79 RB cell viability ranges between 115 and 157 % and 111-126 % after 24 and 48 h of exposures with Antioxidant peptide A, respectively. The cancer cell death from the treatment of 10-100 μM GNPs concentration is studied[1].
SynonymsAntioxidant peptide A acetate (159147-88-3 free base)
Chemical Properties
Molecular Weight831.02
FormulaC33H58N12O9S2
SmilesCC(O)=O.O=C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CS)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCSC)C(O)=O)=O)=O)=O)=O)[C@H]2NCCC2
Relative Density.no data available
SequenceH-Pro-His-Cys-Lys-Arg-Met-OH.TFA
Sequence ShortPHCKRM
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mM, Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2033 mL6.0167 mL12.0334 mL60.1670 mL
5 mM0.2407 mL1.2033 mL2.4067 mL12.0334 mL
10 mM0.1203 mL0.6017 mL1.2033 mL6.0167 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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