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Deoxypseudouridine

Name: Deoxypseudouridine
Brand: TargetMol
SKU: T13645
Rating: 4.5 (1 reviews)

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Catalog No. T13645Cas No. 39967-60-7

Deoxypseudouridine is a nucleotide analog.

Deoxypseudouridine

😃Good

Catalog No. T13645Cas No. 39967-60-7

Deoxypseudouridine is a nucleotide analog.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mL x 10 mM (in DMSO)	$270	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description

Deoxypseudouridine is a nucleotide analog.

In vitro

Deoxypseudouridine is a nucleotide analog. The ethidium bromide staining of the gel showed that both the control DNA and analog DNA samples (including deoxypseudoduduridin) had the same degree of digestion of the carrier DNA. This indicates that the restriction enzyme is as active as unmodified (control) DNA in the presence of modified DNA substrates (including deoxypseudo-rhododendronine). Enzymes that do not contain AT base pairs in their recognition sequences will effectively limit DNA replaced by deoxypseudoduridine or deoxytubercidin like controls.

Chemical Properties

Molecular Weight	228.2
Formula	C₉H₁₂N₂O₅
Cas No.	39967-60-7
Smiles	OC[C@H]1O[C@H](C[C@@H]1O)c1c[nH]c(=O)[nH]c1=O
Relative Density.	1.503 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 37 mg/mL (162.14 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2 mg/mL (8.76 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3821 mL	21.9106 mL	43.8212 mL	219.1060 mL
5 mM	0.8764 mL	4.3821 mL	8.7642 mL	43.8212 mL
10 mM	0.4382 mL	2.1911 mL	4.3821 mL	21.9106 mL
20 mM	0.2191 mL	1.0955 mL	2.1911 mL	10.9553 mL
50 mM	0.0876 mL	0.4382 mL	0.8764 mL	4.3821 mL
100 mM	0.0438 mL	0.2191 mL	0.4382 mL	2.1911 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc