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Synonyms: Interleukin-22a, Interleukin-22, IL-TIF α, IL-TIF alpha, IL-TIF, IL-22a, IL-22, IL22, IL-10-related T-cell-derived-inducible factor

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $80 | - | In Stock | |
| 10 µg | $129 | - | In Stock | |
| 20 µg | $198 | 7-10 days | 7-10 days | |
| 50 µg | $390 | 7-10 days | 7-10 days | |
| 100 µg | $626 | 7-10 days | 7-10 days | |
| 200 µg | $987 | 7-10 days | 7-10 days | |
| 500 µg | $1,900 | 7-10 days | 7-10 days | |
| 1 mg | $2,730 | 7-10 days | 7-10 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | IL-22 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 50-65 KDa and the accession number is Q9JJY9. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-mFc |
| Accession Number | Q9JJY9 |
| Amino Acid | Leu34-Val179 |
| Construction | Leu34-Val179 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) ![]() |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | Interleukin-22a, Interleukin-22, IL-TIF α, IL-TIF alpha, IL-TIF, IL-22a, IL-22, IL22, IL-10-related T-cell-derived-inducible factor |
| Research Background | Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79% and 22% sequence identity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10Rβ (previously known as CRF2-4), belonging to the class II cytokine receptor family. |
| Molecular Weight | 50-65 KDa (reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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