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IL-22 Protein, Mouse, Recombinant (mFc)

(Synonyms: Interleukin-22a, Interleukin-22, IL-TIF α, IL-TIF alpha, IL-TIF, IL-22a, IL-22, IL22, IL-10-related T-cell-derived-inducible factor) Copy Product Info

Synonyms: Interleukin-22a, Interleukin-22, IL-TIF α, IL-TIF alpha, IL-TIF, IL-22a, IL-22, IL22, IL-10-related T-cell-derived-inducible factor

Catalog No. TMPJ-01340 Copy Product Info
IL-22 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 50-65 KDa and the accession number is Q9JJY9.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$80-In Stock
10 µg$129-In Stock
20 µg$1987-10 days7-10 days
50 µg$3907-10 days7-10 days
100 µg$6267-10 days7-10 days
200 µg$9877-10 days7-10 days
500 µg$1,9007-10 days7-10 days
1 mg$2,7307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
IL-22 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 50-65 KDa and the accession number is Q9JJY9.
Species
Mouse
Expression System
HEK293 Cells
TagC-mFc
Accession NumberQ9JJY9
Amino AcidLeu34-Val179
ConstructionLeu34-Val179
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
IL-22 Protein, Mouse, Recombinant (mFc)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsInterleukin-22a, Interleukin-22, IL-TIF α, IL-TIF alpha, IL-TIF, IL-22a, IL-22, IL22, IL-10-related T-cell-derived-inducible factor
Research Background
Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79% and 22% sequence identity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10Rβ (previously known as CRF2-4), belonging to the class II cytokine receptor family.
Chemical Properties
Molecular Weight50-65 KDa (reducing condition)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: IL-22 Protein, Mouse, Recombinant (mFc) chemical structure | IL-22 Protein, Mouse, Recombinant (mFc) molecular weight