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4-CPPC

🥰Excellent
Catalog No. T38293Cas No. 29553-70-6

4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).1It is selective for MIF-2 over MIF-1 (IC50= 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.

4-CPPC

4-CPPC

🥰Excellent
Purity: 98.03%
Catalog No. T38293Cas No. 29553-70-6
4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).1It is selective for MIF-2 over MIF-1 (IC50= 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
Pack SizePriceAvailabilityQuantity
1 mg$51In Stock
5 mg$122In Stock
10 mg$198In Stock
25 mg$455In Stock
50 mg$672In Stock
100 mg$956In Stock
500 mg$1,920In Stock
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Purity:98.03%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).1It is selective for MIF-2 over MIF-1 (IC50= 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
Chemical Properties
Molecular Weight287.22
FormulaC14H9NO6
Cas No.29553-70-6
SmilesOC(=O)C1=CC=CC(=C1)C1=CC(=NC=C1C(O)=O)C(O)=O
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 2.87 mg/mL (9.99 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4817 mL17.4083 mL34.8165 mL174.0826 mL
5 mM0.6963 mL3.4817 mL6.9633 mL34.8165 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

4-CPPC4CPPC4 CPPC
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