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Anti-Desmin Antibody (6C49)
😃Good
Catalog No. TMAY-00114
Alias Desmin, DES
Anti-Desmin Antibody (6C49) is a Mouse antibody targeting Desmin. Anti-Desmin Antibody (6C49) can be used in IHC-P.
Anti-Desmin Antibody (6C49)
Anti-Desmin Antibody (6C49)
😃Good
Catalog No. TMAY-00114Alias Desmin, DES
Anti-Desmin Antibody (6C49) is a Mouse antibody targeting Desmin. Anti-Desmin Antibody (6C49) can be used in IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Desmin Antibody (6C49) is a Mouse antibody targeting Desmin. Anti-Desmin Antibody (6C49) can be used in IHC-P. |
| Synonyms | Desmin, DES |
| Ig Type | Mouse IgG1 |
| Clone | 6C49 |
| Reactivity | Human |
| Specificity | Human Mouse, Rat (Species predicted to react based on 100% sequence homology) |
| Verified Activity | 1. Immunochemical staining of human Desmin in human heart with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human Desmin in human smooth muscle with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections. |
| Application | |
| Recommended Dose | IHC-P: 1:30-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the C-terminus of the Human Desmin. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The cohesin loading factor, nipped-B-like protein (NIPBL), is also known as the sister chromatid cohesion 2 (SCC2) human homolog, is a cohesin loading factor which is essential for deposition of cohesin onto the sister chromatid. Recent studies have shown that NIPBL contributes to sister chromatid cohesion and plays a critical role in development, DNA repair, and gene regulation. Downregulation of NIPBL arrested cells in the G0/G1 phase of the cell cycle and induced apoptosis and autophagy of breast cancer cells through the caspase3 and mammalian target of rapamycin (mTOR) signaling pathways. NIPBL, the sister chromatid cohesion 2 (SCC2) human homolog, is a cohesin loading factor which is essential for deposition of cohesin onto the sister chromatid. Recent studies have shown that NIPBL contributes to sister chromatid cohesion and plays a critical role in development, DNA repair, and gene regulation. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: C-terminus of the Human Desmin |
| Antigen Species | Human |
| Biology Area | Cardiac Stem Cell Markers |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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