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Anti-ASCL2 Polyclonal Antibody
(Synonyms: mASH-2, mASH2, ASH-2, Ascl2, Achaete-scute homolog 2) Copy Product Info
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Synonyms: mASH-2, mASH2, ASH-2, Ascl2, Achaete-scute homolog 2
Catalog No. TMAB-00151 Copy Product Info
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Anti-ASCL2 Polyclonal Antibody is a Rabbit antibody targeting ASCL2. Anti-ASCL2 Polyclonal Antibody can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P.
Anti-ASCL2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ASCL2 Polyclonal Antibody is a Rabbit antibody targeting ASCL2. Anti-ASCL2 Polyclonal Antibody can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P. |
| Synonyms | mASH-2, mASH2, ASH-2, Ascl2, Achaete-scute homolog 2 |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow) |
| Application | |
| Recommended Dose | FCM=2 μg/Test; ICC/IF=1:100-500; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed specifically in the extravillous trophoblasts of the developing placenta. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix (bHLH) transcription factors that function as dominant negative regulators and are involved in cell lineage determination and differentiation. ASCL2 is a 193 amino acid protein that localizes to the nucleus and contains one bHLH domain. Expressed in developing placental tissue, ASCL2 binds to DNA and functions as a transcriptional regulator that is involved in the maturation of neuronal precursors in the peripheral and central nervous systems. |
| Immunogen | KLH conjugated synthetic peptide: Human ASCL2 |
| Antigen Species | Human |
| Gene Name | ASCL2 |
| Gene ID | |
| Protein Name | Achaete-scute homolog 2 |
| Uniprot ID | |
| Function | AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. |
| Molecular Weight | Theoretical: 22 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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