FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 418.00 | |
500 μg | 5 days | $ 1,670.00 | |
1 mg | 5 days | $ 2,800.00 |
Description | FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
Species | Mouse |
Expression System | HEK293 |
Tag | C-His |
Accession Number | Q68SN8-1 |
Synonyms | CD307e, FcRL5, BXMAS1MGC119592, IFGP5, FcRH5, BXMAS1, CD307, DKFZp667F216, FLJ00333, FCRH5MGC119593, DKFZp667E2019, FLJ00397, FcR-like protein 5 |
Construction | Recombinant Mouse FcRH5/FcRL5 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Gln27-Ala496.[Accession |Q68SN8-1] |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | The protein has a predicted MW of 53.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
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Please read the User Guide of Recombinant Proteins for more specific information.
FcRH5/FcRL5 Protein, Mouse, Recombinant (His) CD307e FcRL5 BXMAS 1 BXMAS1MGC119592 IFGP5 FLJ 00333 FcRH5 FCRH5MGC 119593 BXMAS1 BXMAS1MGC-119592 CD 307 DKFZp667F 216 CD307 DKFZp667F216 FLJ-00397 IFGP-5 FLJ00333 BXMAS1MGC 119592 CD-307 DKFZp667E-2019 BXMAS-1 FLJ-00333 FLJ 00397 DKFZp667F-216 FCRH5MGC119593 DKFZp667E 2019 DKFZp667E2019 FLJ00397 IFGP 5 FcR-like protein 5 FCRH5MGC-119593 recombinant recombinant-proteins proteins protein