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Anti-IL-18R alpha Antibody-HRP (6A27)

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Catalog No. TMAY-03103H
Alias interleukin 18 receptor 1, IL-1Rrp, IL1RRP, IL18RA, CDw218a, CD218a

Anti-IL-18R alpha Antibody-HRP (6A27) is a HRP-conjugated Rabbit antibody targeting IL-18R alpha. Anti-IL-18R alpha Antibody-HRP (6A27) can be used in ELISA.

Anti-IL-18R alpha Antibody-HRP (6A27)

Anti-IL-18R alpha Antibody-HRP (6A27)

😃Good
Catalog No. TMAY-03103HAlias interleukin 18 receptor 1, IL-1Rrp, IL1RRP, IL18RA, CDw218a, CD218a
Anti-IL-18R alpha Antibody-HRP (6A27) is a HRP-conjugated Rabbit antibody targeting IL-18R alpha. Anti-IL-18R alpha Antibody-HRP (6A27) can be used in ELISA.
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100 μg$410 7-10 days
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Product Introduction

Bioactivity
Description
Anti-IL-18R alpha Antibody-HRP (6A27) is a HRP-conjugated Rabbit antibody targeting IL-18R alpha. Anti-IL-18R alpha Antibody-HRP (6A27) can be used in ELISA.
Aliasinterleukin 18 receptor 1, IL-1Rrp, IL1RRP, IL18RA, CDw218a, CD218a
Ig Type
Monoclonal Rabbit IgG
Clone
6A27
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 0.1-1 μg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL18R1 (rM IL18R1; TMPY-01376; NP_032391.1; Met1-Gly326), and conjugated with horseradish-peroxidase (HRP).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundInterleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expressed in the lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from the brain, skeletal muscle, pancreas, and kidney. A high level of expression is found in Hodgkin disease cell lines. This receptor is specifically bound to interleukin 18 (IL18) and is essential for IL18 mediated signal transduction. IL18R1 contains 3 Ig-like C2-type (immunoglobulin-like) domains and 1 TIR domain. It is a single-pass type I membrane protein. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. The increased expression of IL18R1 may contribute pathogenically to disease and is therefore a potential therapeutic target. The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
Related Conjugates and Formulations
Conjucates
HRP
Others Formats
Unconjugated
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Mouse IL18R1 Protein (TMPY-01376)
Antigen Species
Mouse
Biology Area
Neuroinflammation
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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