Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KRAS inhibitor-12 (compound 6-1) is a potent inhibitor of KRAS G12C (IC50: 0.537 μM). KRAS inhibitor-12 exhibits p-ERK inhibition in MIA PaCA-2, A549 cells with IC50 values of 1.3, 3.7 μM respectively. KRAS inhibitor-12 has potential to be studied in pancreatic, colorectal and lung cancers.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 2,140.00 | |
50 mg | 8-10 weeks | $ 2,785.00 | |
100 mg | 8-10 weeks | $ 3,520.00 |
Description | KRAS inhibitor-12 (compound 6-1) is a potent inhibitor of KRAS G12C (IC50: 0.537 μM). KRAS inhibitor-12 exhibits p-ERK inhibition in MIA PaCA-2, A549 cells with IC50 values of 1.3, 3.7 μM respectively. KRAS inhibitor-12 has potential to be studied in pancreatic, colorectal and lung cancers. |
Molecular Weight | 452.33 |
Formula | C19H16Cl2FN5OS |
CAS No. | 2230874-00-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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KRAS inhibitor-12 2230874-00-5 inhibitor inhibit