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Poloxamer 235 (P85)

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Catalog No. TSH-00419
Alias 9003-11-6

Poloxamer 235 P85 is a block copolymer composed of polyoxyethylene and polyoxypropylene, with an average molecular weight of 4600. In tests with albino rats, it displays acute and subchronic oral toxicity, with an LD50 greater than 34.6 g/kg. It also causes ocular irritation in rabbits.

Poloxamer 235 (P85)

Poloxamer 235 (P85)

😃Good
Catalog No. TSH-00419Alias 9003-11-6
Poloxamer 235 P85 is a block copolymer composed of polyoxyethylene and polyoxypropylene, with an average molecular weight of 4600. In tests with albino rats, it displays acute and subchronic oral toxicity, with an LD50 greater than 34.6 g/kg. It also causes ocular irritation in rabbits.
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Product Introduction

Bioactivity
Description
Poloxamer 235 P85 is a block copolymer composed of polyoxyethylene and polyoxypropylene, with an average molecular weight of 4600. In tests with albino rats, it displays acute and subchronic oral toxicity, with an LD50 greater than 34.6 g/kg. It also causes ocular irritation in rabbits.
Alias9003-11-6
Chemical Properties
Molecular Weight4600(Averag)
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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