keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 40.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 155.00 | |
25 mg | In stock | $ 313.00 | |
50 mg | In stock | $ 493.00 | |
100 mg | In stock | $ 723.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 94.00 |
Description | Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8. |
In vitro | Boc-Asp(OME)-Fluoromethyl Keton (100 μM; 30 minutes; Polymorphonuclear leukocytes) prevents Fas-induced and spontaneous apoptosis (-CH-11)[1]. Boc-Asp(OME)-Fluoromethyl Keton (20 μM; 5 hours; J774.1/JA-4 cells) significantly increases the release of LDH[2]. |
Synonyms | Boc-Asp(OMe)-fluoromethyl ketone, Boc-Asp(OMe)-FMK |
Molecular Weight | 263.26 |
Formula | C11H18FNO5 |
CAS No. | 187389-53-3 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (227.91 mM)
You can also refer to dose conversion for different animals. More
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Boc-Asp(OMe)-fluoromethyl ketone 187389-53-3 Apoptosis Proteases/Proteasome Caspase inhibit broad Boc Asp(OMe) fluoromethyl ketone Fas-induced Inhibitor LDH oxidative apoptosis spontaneous Boc-Asp(OMe)-FMK BocAsp(OMe)fluoromethyl ketone rupture inhibitor