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Anti-PIEZO1 Polyclonal Antibody
(Synonyms: Protein FAM38A, Piezo-type mechanosensitive ion channel component 1, PIEZO1, Membrane protein induced by beta-amyloid treatment (Mib), KIAA0233, FAM38A) Copy Product Info
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Synonyms: Protein FAM38A, Piezo-type mechanosensitive ion channel component 1, PIEZO1, Membrane protein induced by beta-amyloid treatment (Mib), KIAA0233, FAM38A
Catalog No. TMAB-01536 Copy Product Info
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Anti-PIEZO1 Polyclonal Antibody is a Rabbit antibody targeting PIEZO1. Anti-PIEZO1 Polyclonal Antibody can be used in ICC/IF, IF, IHC-Fr, IHC-P.
Anti-PIEZO1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-PIEZO1 Polyclonal Antibody is a Rabbit antibody targeting PIEZO1. Anti-PIEZO1 Polyclonal Antibody can be used in ICC/IF, IF, IHC-Fr, IHC-P. |
| Synonyms | Protein FAM38A, Piezo-type mechanosensitive ion channel component 1, PIEZO1, Membrane protein induced by beta-amyloid treatment (Mib), KIAA0233, FAM38A |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Dog,Cow,Sheep) |
| Application | |
| Recommended Dose | ICC/IF=1:100-500; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane. Endoplasmic reticulum-Golgi intermediate compartment membrane. Cell membrane. |
| Tissue Specificity | Expressed in numerous tissues. In normal brain, expressed exclusively in neurons, not in astrocytes. In Alzheimer disease brains, expressed in about half of the activated astrocytes located around classical senile plaques. In Parkinson disease substantia |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a mechanically-activated ion channel that links mechanical forces to biological signals. The encoded protein contains 36 transmembrane domains and functions as a homotetramer. Defects in this gene have been associated with dehydrated hereditary stomatocytosis. [provided by RefSeq, Jul 2015] |
| Immunogen | KLH conjugated synthetic peptide: human FAM38A |
| Antigen Species | Human |
| Gene Name | Piezo1 |
| Gene ID | |
| Protein Name | Piezo-type mechanosensitive ion channel component 1 |
| Uniprot ID | |
| Biology Area | ER |
| Function | Component of mechanosensitive channel required for the mechanosensitive currents. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling. |
| Molecular Weight | Theoretical: 287 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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