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Anti-Decorin Antibody (2P567)
😃Good
Catalog No. TMAY-00429
Alias SLRR1B, PGS2, PGII, PG40, DSPG2, decorin, CSCD
Anti-Decorin Antibody (2P567) is a Rabbit antibody targeting Decorin. Anti-Decorin Antibody (2P567) can be used in ELISA.
Anti-Decorin Antibody (2P567)
Anti-Decorin Antibody (2P567)
😃Good
Catalog No. TMAY-00429Alias SLRR1B, PGS2, PGII, PG40, DSPG2, decorin, CSCD
Anti-Decorin Antibody (2P567) is a Rabbit antibody targeting Decorin. Anti-Decorin Antibody (2P567) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | SLRR1B, PGS2, PGII, PG40, DSPG2, decorin, CSCD |
| Ig Type | Rabbit IgG |
| Clone | 2P567 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Decorin (rh Decorin; TMPY-01608; NP_001911.1; Met 1-Lys 359). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core protein and a covalently linked glycosaminoglycan chain which is either chondroitin sulfate (CS) or dermatan sulfate (DS). As a component of connective tissue, decorin interacts with several extracellular matrix components, such as type I collagen and fibronectin, and plays a role in matrix assembly. Decorin resides in the tumor microenvironment and affects the biology of various types of cancer by downregulating the activity of several receptors involved in cell growth and survival. Decorin binds to and modulates the signaling of the epidermal growth factor receptor and other members of the ErbB family of receptor tyrosine kinases. It exerts its antitumor activity by a dual mechanism: via inhibition of these key receptors through their physical downregulation coupled with attenuation of their signaling, and by binding to and sequestering TGFbeta. Decorin also modulates the insulin-like growth factor receptor and the low-density lipoprotein receptor-related protein 1, which indirectly affects the TGFbeta receptor pathway. Decorin plays significant roles in tissue development and assembly, as well as playing both direct and indirect signaling roles. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Decorin protein (TMPY-01608) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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