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Anti-Decorin Antibody (2P567)

😃Good
Catalog No. TMAY-00429
Alias SLRR1B, PGS2, PGII, PG40, DSPG2, decorin, CSCD

Anti-Decorin Antibody (2P567) is a Rabbit antibody targeting Decorin. Anti-Decorin Antibody (2P567) can be used in ELISA.

Anti-Decorin Antibody (2P567)

Anti-Decorin Antibody (2P567)

😃Good
Catalog No. TMAY-00429Alias SLRR1B, PGS2, PGII, PG40, DSPG2, decorin, CSCD
Anti-Decorin Antibody (2P567) is a Rabbit antibody targeting Decorin. Anti-Decorin Antibody (2P567) can be used in ELISA.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Decorin Antibody (2P567) is a Rabbit antibody targeting Decorin. Anti-Decorin Antibody (2P567) can be used in ELISA.
AliasSLRR1B, PGS2, PGII, PG40, DSPG2, decorin, CSCD
Ig Type
Monoclonal Rabbit IgG
Clone
2P567
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Decorin (rh Decorin; TMPY-01608; NP_001911.1; Met 1-Lys 359).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundDecorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core protein and a covalently linked glycosaminoglycan chain which is either chondroitin sulfate (CS) or dermatan sulfate (DS). As a component of connective tissue, decorin interacts with several extracellular matrix components, such as type I collagen and fibronectin, and plays a role in matrix assembly. Decorin resides in the tumor microenvironment and affects the biology of various types of cancer by downregulating the activity of several receptors involved in cell growth and survival. Decorin binds to and modulates the signaling of the epidermal growth factor receptor and other members of the ErbB family of receptor tyrosine kinases. It exerts its antitumor activity by a dual mechanism: via inhibition of these key receptors through their physical downregulation coupled with attenuation of their signaling, and by binding to and sequestering TGFbeta. Decorin also modulates the insulin-like growth factor receptor and the low-density lipoprotein receptor-related protein 1, which indirectly affects the TGFbeta receptor pathway. Decorin plays significant roles in tissue development and assembly, as well as playing both direct and indirect signaling roles.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Decorin protein (TMPY-01608)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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