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Talaporfin sodium

Name: Talaporfin sodium
Brand: TargetMol
SKU: T16978
Rating: 4.5 (1 reviews)

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Catalog No. T16978Cas No. 220201-34-3

Alias NPe6, Mono-L-aspartyl chlorin e6, ME2906

Talaporfin is a photosensitizer used in photodynamic therapy.

Talaporfin sodium

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Catalog No. T16978Alias NPe6, Mono-L-aspartyl chlorin e6, ME2906Cas No. 220201-34-3

Talaporfin is a photosensitizer used in photodynamic therapy.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$1,750	4-6 weeks	4-6 weeks
50 mg	$2,440	4-6 weeks	4-6 weeks
100 mg	$2,960	4-6 weeks	4-6 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Talaporfin is a photosensitizer used in photodynamic therapy.
In vitro	Talaporfin is a photosensitizer used in photodynamic therapy. Talaporfin absorbs red light at 664 nm normally provided by a laser tuned to this wavelength. Talaporfin was approved in Japan (in 2004) for PDT of lung cancer and marketed as Laserphyrin [1][2].
Synonyms	NPe6, Mono-L-aspartyl chlorin e6, ME2906

Chemical Properties

Molecular Weight	734.762
Formula	C₃₈H₄₁N₅NaO₉
Cas No.	220201-34-3
Smiles	[Na].CCc1c(C)c2cc3[nH]c(cc4nc([C@@H](CCC(O)=O)[C@@H]4C)c(CC(=O)N[C@@H](CC(O)=O)C(O)=O)c4[nH]c(cc1n2)c(C)c4C(O)=O)c(C)c3C=C \|w:23.23,11.10,7.5,39.38\|jcExt:v:0:0
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 2 mg/mL (2.72 mM), Sonication is recommended.

H2O: 50 mg/mL (68.05 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	1.3610 mL	6.8049 mL	13.6098 mL	68.0492 mL

H2O

	1mg	5mg	10mg	50mg
5 mM	0.2722 mL	1.3610 mL	2.7220 mL	13.6098 mL
10 mM	0.1361 mL	0.6805 mL	1.3610 mL	6.8049 mL
20 mM	0.0680 mL	0.3402 mL	0.6805 mL	3.4025 mL
50 mM	0.0272 mL	0.1361 mL	0.2722 mL	1.3610 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc