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Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His)
(Synonyms: Platelet-Activating Factor Acetylhydrolase, PAF Acetylhydrolase, PAF 2-Ac, LDL-PLA(2), LDL-Associated Phospholipase A2, gVIIA-PLA2, Group-VIIA Phospholipase A2, 2-Acetyl-1-Alkylglycerophosphocholine Esterase, 1-Alkyl-2-Acetylglycerophosphocholine Esterase) Copy Product InfoSynonyms: Platelet-Activating Factor Acetylhydrolase, PAF Acetylhydrolase, PAF 2-Ac, LDL-PLA(2), LDL-Associated Phospholipase A2, gVIIA-PLA2, Group-VIIA Phospholipase A2, 2-Acetyl-1-Alkylglycerophosphocholine Esterase, 1-Alkyl-2-Acetylglycerophosphocholine Esterase
Catalog No. TMPJ-00553 Copy Product Info
Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive products. PAFAH is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. PAFAH has been implicated in the development of atherosclerosis and has also been identified as a marker for cardiac disease. PAFAH might have a major physiologic effect in the presence of inflammatory bodily responses. PAFAH alters the action of PAF by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. PAFAH has specificity for substrates with a short residue at the sn-2 position.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $112 | 7-10 days | 7-10 days | |
| 10 μg | $183 | 7-10 days | 7-10 days | |
| 20 μg | $292 | 7-10 days | 7-10 days | |
| 50 μg | $545 | 7-10 days | 7-10 days | |
| 100 μg | $792 | 7-10 days | 7-10 days | |
| 200 μg | $1,150 | 7-10 days | 7-10 days | |
| 500 μg | $1,900 | 7-10 days | 7-10 days | |
| 1 mg | $2,730 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:Greater than 90% as determined by reducing SDS-PAGE.
Appearance:Liquid
Color:Transparent
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Product Introduction
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Storage & Solubility Information
| Description | Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive products. PAFAH is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. PAFAH has been implicated in the development of atherosclerosis and has also been identified as a marker for cardiac disease. PAFAH might have a major physiologic effect in the presence of inflammatory bodily responses. PAFAH alters the action of PAF by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. PAFAH has specificity for substrates with a short residue at the sn-2 position. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-6xHis |
| Accession Number | AAH38452.1 |
| Amino Acid | Phe22-Asn441 |
| Construction | Phe22-Asn441 |
| Protein Purity | Greater than 90% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 50 mM NaAc, 150 mM NaCl, 50% Glycerol, pH5.0. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | Platelet-Activating Factor Acetylhydrolase, PAF Acetylhydrolase, PAF 2-Ac, LDL-PLA(2), LDL-Associated Phospholipase A2, gVIIA-PLA2, Group-VIIA Phospholipase A2, 2-Acetyl-1-Alkylglycerophosphocholine Esterase, 1-Alkyl-2-Acetylglycerophosphocholine Esterase |
| Research Background |
| Molecular Weight | 50-65 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Related Tags: Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His) chemical structure | Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His) molecular weight
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