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2-Acetylthiophene thiosemicarbazone

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Catalog No. T35680Cas No. 5351-71-3
Alias ATTSC, 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide

2-Acetylthiophene thiosemicarbazone is an antimicrobial agent that exhibits antimicrobial activity against a wide range of gram-negative (E. coli, P. aeruginosa, and S. marcescens ) and gram-positive (S. aureus, M. luteus, and B. cereus) bacteria. In addition, it has antimicrobial activity against a wide range of fungi (C. albicans, G. candidum, T. rubrum, F. oxysporum, A. flavus, and S. brevicaulis).

2-Acetylthiophene thiosemicarbazone

2-Acetylthiophene thiosemicarbazone

😃Good
Catalog No. T35680Alias ATTSC, 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamideCas No. 5351-71-3
2-Acetylthiophene thiosemicarbazone is an antimicrobial agent that exhibits antimicrobial activity against a wide range of gram-negative (E. coli, P. aeruginosa, and S. marcescens ) and gram-positive (S. aureus, M. luteus, and B. cereus) bacteria. In addition, it has antimicrobial activity against a wide range of fungi (C. albicans, G. candidum, T. rubrum, F. oxysporum, A. flavus, and S. brevicaulis).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$15935 days35 days
10 mg$29735 days35 days
25 mg$68635 days35 days
50 mg$1,28035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
2-Acetylthiophene thiosemicarbazone is an antimicrobial agent that exhibits antimicrobial activity against a wide range of gram-negative (E. coli, P. aeruginosa, and S. marcescens ) and gram-positive (S. aureus, M. luteus, and B. cereus) bacteria. In addition, it has antimicrobial activity against a wide range of fungi (C. albicans, G. candidum, T. rubrum, F. oxysporum, A. flavus, and S. brevicaulis).
SynonymsATTSC, 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide
Chemical Properties
Molecular Weight199.3
FormulaC7H9N3S2
Cas No.5351-71-3
SmilesS=C(N)NN=C(C=1SC=CC1)C
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: < 1?mg/mL?(insoluble?or?slightly?soluble), < 0.1 mg/mL (insoluble)
DMSO:PBS (pH 7.2) (1:4): < 1?mg/mL?(insoluble?or?slightly?soluble), < 0.1 mg/mL (insoluble)
DMSO: 20 mg/mL (100.35 mM), Sonication is recommended.
DMF: 20 mg/mL (100.35 mM), Sonication is recommended.
Solution Preparation Table
DMSO/DMF
1mg5mg10mg50mg
1 mM5.0176 mL25.0878 mL50.1756 mL250.8781 mL
5 mM1.0035 mL5.0176 mL10.0351 mL50.1756 mL
10 mM0.5018 mL2.5088 mL5.0176 mL25.0878 mL
20 mM0.2509 mL1.2544 mL2.5088 mL12.5439 mL
50 mM0.1004 mL0.5018 mL1.0035 mL5.0176 mL
100 mM0.0502 mL0.2509 mL0.5018 mL2.5088 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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