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TargetMol | Tags Metabolism
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N-Acetylglucosaminyltransferase

In enzymology, a protein N-acetylglucosaminyltransferase is an enzyme that catalyzes the chemical reaction,the two substrates of this enzyme are UDP-N-acetyl-D-glucosamine and protein, whereas its two products are UDP and 4-N-(N-acetyl-D-glucosaminyl)-protein.This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine:protein beta-N-acetyl-D-glucosaminyl-transferase. Other names in common use include uridine diphosphoacetylglucosamine-protein, acetylglucosaminyltransferase, uridine diphospho-N-acetylglucosamine:polypeptide, beta-N-acetylglucosaminyltransferase, and O-GlcNAc transferase.

FilterHomeSignaling PathwaysMetabolismN-Acetylglucosaminyltransferase
Talniflumate
T450366898-62-2
Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome.
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