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MMP-7-IN-2

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Catalog No. T78181Cas No. 2848717-49-5

MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.

MMP-7-IN-2

MMP-7-IN-2

😃Good
Purity: 97.82%
Catalog No. T78181Cas No. 2848717-49-5
MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$253-In Stock
5 mg$622-In Stock
10 mg$1,120-In Stock
25 mg$1,660-In Stock
50 mg$2,230-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:97.82%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.
Targets&IC50
MMP7:16 nM, MMP14:11000 nM, MMP3:>100000, MMP2:33000 nM, MMP13:>100000, MMP12:12000 nM, MMP9:>100000, MMP8:>100000
Chemical Properties
Molecular Weight729.17
FormulaC28H40ClF3N6O9S
Cas No.2848717-49-5
SmilesS(N[C@@H](CCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)C)=O)C(C)C)=O)CC(C)C)=O)=O)C(O)=O)(=O)(=O)C1=CC(C(F)(F)F)=C(Cl)C=C1
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (109.71 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.3714 mL6.8571 mL13.7142 mL68.5711 mL
5 mM0.2743 mL1.3714 mL2.7428 mL13.7142 mL
10 mM0.1371 mL0.6857 mL1.3714 mL6.8571 mL
20 mM0.0686 mL0.3429 mL0.6857 mL3.4286 mL
50 mM0.0274 mL0.1371 mL0.2743 mL1.3714 mL
100 mM0.0137 mL0.0686 mL0.1371 mL0.6857 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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