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Anti-IL-23 P19/IL23A Antibody (4S598) is an antibody targeting IL-23 P19/IL23A. Anti-IL-23 P19/IL23A Antibody (4S598) can be used in ELISA,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
| Description | Anti-IL-23 P19/IL23A Antibody (4S598) is an antibody targeting IL-23 P19/IL23A. Anti-IL-23 P19/IL23A Antibody (4S598) can be used in ELISA,WB. |
| Synonyms | SGRF, P19, interleukin 23, α subunit p19, interleukin 23, alpha subunit p19, IL23P19, IL-23A, IL-23 |
| Ig Type | Rabbit IgG |
| Clone | 4S598 |
| Reactivity | Human |
| Verified Activity | Western Blot -Positive WB detected in: THP-1 whole cell lysate -All lanes: IL23 antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 21 kDa -Observed band size: 21 kDa |
| Application | |
| Recommended Dose | WB:1:500-1:5000. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted. Note=Secreted upon association with IL12B. |
| Tissue Specificity | Secreted by activated dendritic and phagocytic cells and keratinocytes. Also expressed by dermal Langerhans cells (at protein level). |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human IL23 |
| Antigen Species | Human |
| Gene Name | IL23A |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer, Immunology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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