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CD79B Protein, Human, Recombinant (hFc)

Catalog No. TMPJ-00113
Synonyms: Immunoglobulin-Associated B29 Protein, B-Cell-Specific Glycoprotein B29, B-Cell Antigen Receptor Complex-Associated Protein Beta Chain, IGB, B-Cell Antigen Receptor Complex-Associated Protein β Chain, Ig-β, B29, CD79b, Ig-Beta

CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CD79B Protein, Human, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
10 μg In stock $ 45.00
50 μg 5 days $ 138.00
500 μg 5 days $ 1,070.00
1 mg 5 days $ 2,510.00
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Biological Description
Technical Params
Product Properties
Biological Information Loaded Human CD79B-Fc on APS Biosensor, can bind Anti-Human CD79B mAb-Fc with an affinity constant of 0.4 nM as determined in BLI assay. (Regularly tested)

Description CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.
Species Human
Expression System Human Cells
Tag C-Fc
Accession Number P40259
Synonyms Immunoglobulin-Associated B29 Protein, B-Cell-Specific Glycoprotein B29, B-Cell Antigen Receptor Complex-Associated Protein Beta Chain, IGB, B-Cell Antigen Receptor Complex-Associated Protein β Chain, Ig-β, B29, CD79b, Ig-Beta
Amino Acid Ala29-Asp159
Construction Recombinant Human CD79B is produced by our Mammalian expression system and the target gene encoding Ala29-Asp159 is expressed with a human IgG1 Fc tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)

Molecular Weight 45-65 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.

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Keywords

CD79B Protein, Human, Recombinant (hFc) Immunoglobulin-Associated B29 Protein B-Cell-Specific Glycoprotein B29 B 29 B-Cell Antigen Receptor Complex-Associated Protein Beta Chain B-29 IGB B-Cell Antigen Receptor Complex-Associated Protein β Chain Ig-β B29 CD79b Ig-Beta recombinant recombinant-proteins proteins protein

 

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