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CD79B Protein, Human, Recombinant (hFc)

TargetMol | SPR
Catalog No. TMPJ-00113 Copy Product Info
CD79B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-65 KDa and the accession number is P40259.

CD79B Protein, Human, Recombinant (hFc)

Catalog No. TMPJ-00113
Copy Product Info
TargetMol | SPR

CD79B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-65 KDa and the accession number is P40259.

CD79B Protein, Human, Recombinant (hFc)
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$317-10 days7-10 days
10 μg$45-In Stock
20 μg$717-10 days7-10 days
50 μg$1387-10 days7-10 days
100 μg$2527-10 days7-10 days
200 μg$4677-10 days7-10 days
500 μg$1,0707-10 days7-10 days
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In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Information

Biological Activity
Loaded Human CD79B-Fc on APS Biosensor, can bind Anti-Human CD79B mAb-Fc with an affinity constant of 0.4 nM as determined in BLI assay. (Regularly tested)
CD79B Protein, Human, Recombinant (hFc)
Description
CD79B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-65 KDa and the accession number is P40259.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberP40259
Synonyms
Immunoglobulin-Associated B29 Protein,Ig-β,Ig-Beta,IGB,CD79b,B-Cell-Specific Glycoprotein B29,B-Cell Antigen Receptor Complex-Associated Protein β Chain,B-Cell Antigen Receptor Complex-Associated Protein Beta Chain,B29
Amino Acid
Ala29-Asp159
Construction
Ala29-Asp159
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
CD79B Protein, Human, Recombinant (hFc)
Molecular Weight45-65 KDa (reducing condition)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background
CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.

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