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Anti-ADAMTS5 Polyclonal Antibody
(Synonyms: Implantin, Aggrecanase-2, ADMP-2, ADAMTS-5, ADAM-TS5, Adamts5, ADAM-TS 5, A disintegrin and metalloproteinase with thrombospondin motifs 5) Copy Product Info
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Synonyms: Implantin, Aggrecanase-2, ADMP-2, ADAMTS-5, ADAM-TS5, Adamts5, ADAM-TS 5, A disintegrin and metalloproteinase with thrombospondin motifs 5
Catalog No. TMAB-00057 Copy Product Info
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Anti-ADAMTS5 Polyclonal Antibody is a Rabbit antibody targeting ADAMTS5. Anti-ADAMTS5 Polyclonal Antibody can be used in ELISA, WB.
Anti-ADAMTS5 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-ADAMTS5 Polyclonal Antibody is a Rabbit antibody targeting ADAMTS5. Anti-ADAMTS5 Polyclonal Antibody can be used in ELISA, WB. |
| Synonyms | Implantin, Aggrecanase-2, ADMP-2, ADAMTS-5, ADAM-TS5, Adamts5, ADAM-TS 5, A disintegrin and metalloproteinase with thrombospondin motifs 5 |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | ELISA=1:5000-10000; WB=1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Expressed at low level in placenta primarily but also detected in heart and brain, cervix, uterus, bladder, esophagus, rib cartilage, chondroblastoma, fibrous tissue and a joint capsule from an arthritic patient. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016] |
| Immunogen | KLH conjugated synthetic peptide: human ADAMTS5 |
| Antigen Species | Human |
| Gene Name | ADAMTS5 |
| Gene ID | |
| Protein Name | A disintegrin and metalloproteinase with thrombospondin motifs 5 |
| Uniprot ID | |
| Biology Area | Aggrecan,MMP,ADAM Protein Family,ADAM TS |
| Function | Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period. |
| Molecular Weight | Theoretical: 102 kDa. Actual: 102 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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