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Podocarpic acid

Name: Podocarpic acid
Brand: TargetMol
SKU: T12514
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12514Cas No. 5947-49-9

Podocarpic acid is a natural product and a novel TRPA1 activator.

Podocarpic acid

😃Good

Purity: 99.55%

Catalog No. T12514Cas No. 5947-49-9

Podocarpic acid is a natural product and a novel TRPA1 activator.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$34	In Stock	In Stock
10 mg	$56	In Stock	In Stock
25 mg	$92	In Stock	In Stock
50 mg	$133	In Stock	-
100 mg	$198	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.55%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Podocarpic acid is a natural product and a novel TRPA1 activator.
In vitro	Podocarpic acid activates SKN-1 in C. elegans, similar to known Nrf2 activators such as α-lipoic acid (LA)[1].
In vivo	Podocarpic acid and LA alleviate the Podocarpic acidthogenic phenotypes of glod-4 animals by reverting the high endogenous MGO and GO to almost wild-type-like levels[1].

Chemical Properties

Molecular Weight	274.35
Formula	C₁₇H₂₂O₃
Cas No.	5947-49-9
Smiles	[H][C@@]12CCc3ccc(O)cc3[C@@]1(C)CCC[C@]2(C)C(O)=O
Relative Density.	1.182 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (364.5 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (14.58 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6450 mL	18.2249 mL	36.4498 mL	182.2490 mL
5 mM	0.7290 mL	3.6450 mL	7.2900 mL	36.4498 mL
10 mM	0.3645 mL	1.8225 mL	3.6450 mL	18.2249 mL
20 mM	0.1822 mL	0.9112 mL	1.8225 mL	9.1124 mL
50 mM	0.0729 mL	0.3645 mL	0.7290 mL	3.6450 mL
100 mM	0.0364 mL	0.1822 mL	0.3645 mL	1.8225 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc