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Endixaprine

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Catalog No. T67954Cas No. 93181-85-2
Alias SR 41378

Endixaprine (SR 41378) is a small molecule compound used to treat neurological disorders and may be used to study anxiety disorders and epilepsy.

Endixaprine

Endixaprine

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Purity: 99.83%
Catalog No. T67954Alias SR 41378Cas No. 93181-85-2
Endixaprine (SR 41378) is a small molecule compound used to treat neurological disorders and may be used to study anxiety disorders and epilepsy.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$46In StockIn Stock
5 mg$106In StockIn Stock
10 mg$156In StockIn Stock
25 mg$303In StockIn Stock
50 mg$413In StockIn Stock
100 mg$589-In Stock
200 mg$797-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.83%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Endixaprine (SR 41378) is a small molecule compound used to treat neurological disorders and may be used to study anxiety disorders and epilepsy.
In vivo
Oral administration of Endixaprin in mice has anticonvulsant activity with an ED50 of 11 mg/kg in tonic epilepsy.[1]
SynonymsSR 41378
Chemical Properties
Molecular Weight324.21
FormulaC15H15Cl2N3O
Cas No.93181-85-2
SmilesClC1=C(C=CC(Cl)=C1)C2=CC=C(N=N2)N3CCC(O)CC3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (138.8 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0844 mL15.4221 mL30.8442 mL154.2210 mL
5 mM0.6169 mL3.0844 mL6.1688 mL30.8442 mL
10 mM0.3084 mL1.5422 mL3.0844 mL15.4221 mL
20 mM0.1542 mL0.7711 mL1.5422 mL7.7111 mL
50 mM0.0617 mL0.3084 mL0.6169 mL3.0844 mL
100 mM0.0308 mL0.1542 mL0.3084 mL1.5422 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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