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Anti-CD155/PVR Antibody-FITC (2B632) is a FITC-conjugated Mouse antibody targeting CD155/PVR. Anti-CD155/PVR Antibody-FITC (2B632) can be used in FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 T | $81 | 7-10 days | |
100 T | $257 | 7-10 days |
Description | Anti-CD155/PVR Antibody-FITC (2B632) is a FITC-conjugated Mouse antibody targeting CD155/PVR. Anti-CD155/PVR Antibody-FITC (2B632) can be used in FCM. |
Alias | TAGE4, PVS, poliovirus receptor, Necl-5, NECL5, HVED, CD155 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 2B632 |
Reactivity | Human |
Verified Activity | 1. Profile of CD155 reactivity on HeLa cells analyzed by flow cytometry. 2. Immunofluorescence staining of Human CD155 in A549 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Mouse anti-Human CD155 monoclonal antibody (FITC-conjugated, 10 µg/ml) at 4°C overnight, and counterstained with DAPI (blue). Positive staining was localized to plasma membrane. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD155 / PVR (rh CD155 / PVR; TMPY-01386; P15151-1; Met 1-Asn 343) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
Research Background | CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhesion, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
Conjucates | FITC |
Others Formats | Unconjugated/APC/PE |
Antibody Types Available | 4 |
Immunogen | Recombinant Human CD155 protein (TMPY-01386) |
Antigen Species | Human |
Biology Area | Cancer Drug Targets |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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