IL-5 Protein, Human, Recombinant (His)

Name: IL-5 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-05576
Price: 54 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: TRF, interleukin 5, IL-5, EDF) Copy Product Info

Synonyms: TRF, interleukin 5, IL-5, EDF

Catalog No. TMPY-05576 Copy Product Info

Purity: 97.7%

IL-5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.6 kDa and the accession number is P05113.

Pack Size	Price	USA Stock	Global Stock
5 µg	$54	-	In Stock
10 µg	$85	-	In Stock
20 µg	$137	-	In Stock
50 µg	$267	-	In Stock
100 µg	$447	-	In Stock
200 µg	$732	7-10 days	7-10 days
500 µg	$1,400	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:97.7%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.2-1.2 ng/mL.
Description	IL-5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.6 kDa and the accession number is P05113.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	P05113
Construction	A DNA sequence encoding the human IL5 (NP_000870.1) (Met1-Ser134) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Ile 20
Protein Purity	> 95 % as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	TRF, interleukin 5, IL-5, EDF
Research Background	Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes) and has been found in a wide variety of body cells. Interleukin 5 or IL-5 is produced by T helper-2 cells and mast cells. It helps to stimulate B cell growth and increase immunoglobulin secretion and is considered a key mediator in eosinophil activation. Interleukin 5 (IL-5) has long been associated with several allergic diseases, including allergic rhinitis and asthma. Growth in the number of circulating, airway tissue, and induced sputum eosinophils have been observed in patients with these diseases. IL-5 also had something with the terminally differentiated granulocyte eosinophils. IL-5 was originally found as an eosinophil colony-stimulating factor. It has been proved to be a major regulator of eosinophil accumulation in tissues and can modulate eosinophil behavior at every stage from maturation to survival.

Chemical Properties

Molecular Weight

14.6 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.