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Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)

Catalog No. TMPY-00570
Synonyms: ALPI, PALP, PLAP, PLAP-1, alkaline phosphatase, placental, IAP, ALP

Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.

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Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
50 μg In stock $ 386.00
100 μg 5 days $ 682.00
200 μg 5 days $ 1,200.00
500 μg 5 days $ 2,540.00
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Biological Description
Technical Params
Product Properties
Biological Information Testing in progress
Description Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.
Species Human
Expression System Yeast
Tag His
Accession Number AAH09647.1
Synonyms ALPI, PALP, PLAP, PLAP-1, alkaline phosphatase, placental, IAP, ALP
Construction A DNA sequence encoding human ALPP (AAH09647.1) (Ile23-Asp506) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity > 80 % as determined by SDS-PAGE

Molecular Weight Approxiamtely 54.1 kDa
Endotoxin Please contact us for more information.
Formulation Supplied as sterile 50 mM Tris-Acetate, 1 mM EDTA, 20 % glycerol, pH 7.5. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

Solution. It is shipped out with blue ice.

Research Background Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.

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Keywords

Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) ALPI PLAP1 PLAP 1 PALP PLAP PLAP-1 alkaline phosphatase, placental IAP ALP recombinant recombinant-proteins proteins protein

 

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