Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)

Catalog No. TMPY-00570

Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.

Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)

Catalog No. TMPY-00570

Pack Size	Price	Availability
50 μg	$386	In Stock
100 μg	$682	7-10 days
200 μg	$1,200	7-10 days
500 μg	$2,540	7-10 days

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COA User Guide of Recombinant Proteins

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Information

Biological Activity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.
Species	Human
Expression System	P. pastoris (Yeast)
Tag	C-His
Accession Number	AAH09647.1
Synonyms	PLAP-1,PLAP,PALP,IAP,ALPI,ALP,alkaline phosphatase, placental
Construction	A DNA sequence encoding human ALPP (AAH09647.1) (Ile23-Asp506) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Ile 23
Protein Purity	> 80 % as determined by SDS-PAGE
Molecular Weight	54.1 kDa (predicted); 66 kDa (reducing conditions)
Endotoxin	Please contact us for more information.
Formulation	Supplied as sterile 50 mM Tris-Acetate, 1 mM EDTA, 20% glycerol, pH 7.5.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.