Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 μg | In stock | $ 386.00 | |
100 μg | 5 days | $ 682.00 | |
200 μg | 5 days | $ 1,200.00 | |
500 μg | 5 days | $ 2,540.00 |
Biological Information | Testing in progress |
Description | Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta. |
Species | Human |
Expression System | Yeast |
Tag | His |
Accession Number | AAH09647.1 |
Synonyms | ALPI, PALP, PLAP, PLAP-1, alkaline phosphatase, placental, IAP, ALP |
Construction | A DNA sequence encoding human ALPP (AAH09647.1) (Ile23-Asp506) was expressed with a polyhistidine tag at the C-terminus. |
Protein Purity |
> 80 % as determined by SDS-PAGE
|
Molecular Weight | Approxiamtely 54.1 kDa |
Endotoxin | Please contact us for more information. |
Formulation | Supplied as sterile 50 mM Tris-Acetate, 1 mM EDTA, 20 % glycerol, pH 7.5. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hard copy of CoA. |
Reconstitution | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
Stability & Storage |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Shipping |
Solution. It is shipped out with blue ice. |
Research Background | Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta. |
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Please read the User Guide of Recombinant Proteins for more specific information.
Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) ALPI PLAP1 PLAP 1 PALP PLAP PLAP-1 alkaline phosphatase, placental IAP ALP recombinant recombinant-proteins proteins protein