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Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
(Synonyms: PLAP-1, PLAP, PALP, IAP, ALPI, ALP, alkaline phosphatase, placental) Copy Product InfoSynonyms: PLAP-1, PLAP, PALP, IAP, ALPI, ALP, alkaline phosphatase, placental
Catalog No. TMPY-00570 Copy Product Info
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $75 | - | In Stock | |
| 10 µg | $118 | - | In Stock | |
| 20 µg | $196 | - | In Stock | |
| 50 µg | $386 | - | In Stock | |
| 100 µg | $682 | 7-10 days | 7-10 days | |
| 200 µg | $1,200 | 7-10 days | 7-10 days | |
| 500 µg | $2,530 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:92.7%
Appearance:Solution
Color:Transparent
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Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta. |
| Species | Human |
| Expression System | P. pastoris (Yeast) |
| Tag | C-His |
| Accession Number | AAH09647.1 |
| Construction | A DNA sequence encoding human ALPP (AAH09647.1) (Ile23-Asp506) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Ile 23 |
| Protein Purity | > 80 % as determined by SDS-PAGE  |
| Endotoxin | Please contact us for more information. |
| Formulation | Supplied as sterile 50 mM Tris-Acetate, 1 mM EDTA, 20% glycerol, pH 7.5. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Synonyms | PLAP-1, PLAP, PALP, IAP, ALPI, ALP, alkaline phosphatase, placental |
| Research Background | Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta. |
| Molecular Weight | 54.1 kDa (predicted); 66 kDa (reducing conditions) |
| Shipping | Proteins are shipped with blue ice. |
| Storage | It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) chemical structure | Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) molecular weight
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