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Anti-CD45 Antibody (2I372)
😃Good
Catalog No. TMAY-00127
Alias T200, protein tyrosine phosphatase, receptor type, C, LY5, L-CA, LCA, GP180, CD45R, CD45, B220
Anti-CD45 Antibody (2I372) is a Rabbit antibody targeting CD45. Anti-CD45 Antibody (2I372) can be used in IHC-P.
Anti-CD45 Antibody (2I372)
Anti-CD45 Antibody (2I372)
😃Good
Catalog No. TMAY-00127Alias T200, protein tyrosine phosphatase, receptor type, C, LY5, L-CA, LCA, GP180, CD45R, CD45, B220
Anti-CD45 Antibody (2I372) is a Rabbit antibody targeting CD45. Anti-CD45 Antibody (2I372) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $94 | 7-10 days | |
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD45 Antibody (2I372) is a Rabbit antibody targeting CD45. Anti-CD45 Antibody (2I372) can be used in IHC-P. |
| Alias | T200, protein tyrosine phosphatase, receptor type, C, LY5, L-CA, LCA, GP180, CD45R, CD45, B220 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2I372 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human LCA in human spleen with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human LCA in human lymphoma with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the C-terminus of the Human CD45/PTPRC. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. CD45 is found expression specifically in hemotopietic cells. CD45 consists of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. It serves as an essential regulator of T-cell and B-cell antigen receptor signaling through either direct interaction with components of the antigen receptor complexes or by activating various Src family kinases required for the antigen receptor signaling and it also can suppress JAK kinases. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human CD45/PTPRC |
| Antigen Species | Human |
| Biology Area | Phosphatases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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