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Anti-TLR1 Polyclonal Antibody
(Synonyms: Toll-like receptor 1, Toll/Interleukin 1 receptor like, Toll(Drosophila) homolog, Toll like receptor 1 Precursor, TLR 1, TIL, Similar to Drosophila Toll protein, rsc786, GD2:CD281, CD281 antigen) Copy Product Info
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Synonyms: Toll-like receptor 1, Toll/Interleukin 1 receptor like, Toll(Drosophila) homolog, Toll like receptor 1 Precursor, TLR 1, TIL, Similar to Drosophila Toll protein, rsc786, GD2:CD281, CD281 antigen
Catalog No. TMAB-01850 Copy Product Info
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Anti-TLR1 Polyclonal Antibody is a Rabbit antibody targeting TLR1. Anti-TLR1 Polyclonal Antibody can be used in FCM, IHC-Fr, IHC-P.
Anti-TLR1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-TLR1 Polyclonal Antibody is a Rabbit antibody targeting TLR1. Anti-TLR1 Polyclonal Antibody can be used in FCM, IHC-Fr, IHC-P. |
| Synonyms | Toll-like receptor 1, Toll/Interleukin 1 receptor like, Toll(Drosophila) homolog, Toll like receptor 1 Precursor, TLR 1, TIL, Similar to Drosophila Toll protein, rsc786, GD2:CD281, CD281 antigen |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Dog,Cow,Horse) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; FCM: 1μg /test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein (By similarity). Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein (By similarity). |
| Tissue Specificity | Ubiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | TLR1 is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The gene encoding TLR1 is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. |
| Immunogen | KLH conjugated synthetic peptide: human TLR1 |
| Antigen Species | Human |
| Gene Name | TLR1 |
| Gene ID | |
| Protein Name | Toll-like receptor 1 |
| Uniprot ID | |
| Biology Area | Receptors,Macrophage / Inflamm.,TLR Signaling,Transmembrane,NFkB Pathway |
| Function | Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). |
| Molecular Weight | Theoretical: 87(hu,mo)/91(rat kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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