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Anti-CCR1/CD191 Polyclonal Antibody
😃Good
Catalog No. TMAB-00321
Alias SCYAR1, MIP1aR, HM145, CMKR1, CMKBR1, CKR-1, CKR1, CD191, CCR-1
Anti-CCR1/CD191 Polyclonal Antibody is a Rabbit antibody targeting CCR1/CD191. Anti-CCR1/CD191 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-CCR1/CD191 Polyclonal Antibody
Anti-CCR1/CD191 Polyclonal Antibody
😃Good
Catalog No. TMAB-00321Alias SCYAR1, MIP1aR, HM145, CMKR1, CMKBR1, CKR-1, CKR1, CD191, CCR-1
Anti-CCR1/CD191 Polyclonal Antibody is a Rabbit antibody targeting CCR1/CD191. Anti-CCR1/CD191 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $220 | 7-10 days | |
| 100 μL | $374 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CCR1/CD191 Polyclonal Antibody is a Rabbit antibody targeting CCR1/CD191. Anti-CCR1/CD191 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Alias | SCYAR1, MIP1aR, HM145, CMKR1, CMKBR1, CKR-1, CKR1, CD191, CCR-1 |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat) |
| Verified Activity | Tissue/cell: human gastric carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-CCR1 Polyclonal Antibody, Unconjugated (TMAB-00321) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human CCR-1 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Beta Chemokine Rec. (CCR),SARS Coronavirus |
| Molecular Weight | Theoretical: 40 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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