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Anti-CCR1/CD191 Polyclonal Antibody

😃Good
Catalog No. TMAB-00321
Alias SCYAR1, MIP1aR, HM145, CMKR1, CMKBR1, CKR-1, CKR1, CD191, CCR-1

Anti-CCR1/CD191 Polyclonal Antibody is a Rabbit antibody targeting CCR1/CD191. Anti-CCR1/CD191 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-CCR1/CD191 Polyclonal Antibody

Anti-CCR1/CD191 Polyclonal Antibody

😃Good
Catalog No. TMAB-00321Alias SCYAR1, MIP1aR, HM145, CMKR1, CMKBR1, CKR-1, CKR1, CD191, CCR-1
Anti-CCR1/CD191 Polyclonal Antibody is a Rabbit antibody targeting CCR1/CD191. Anti-CCR1/CD191 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceAvailabilityQuantity
50 μL$2207-10 days
100 μL$3747-10 days
200 μL$5277-10 days
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Product Introduction

Bioactivity
Description
Anti-CCR1/CD191 Polyclonal Antibody is a Rabbit antibody targeting CCR1/CD191. Anti-CCR1/CD191 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
AliasSCYAR1, MIP1aR, HM145, CMKR1, CMKBR1, CKR-1, CKR1, CD191, CCR-1
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat)
Verified Activity
Tissue/cell: human gastric carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-CCR1 Polyclonal Antibody, Unconjugated (TMAB-00321) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
Application
IHC-P,IHC-Fr,IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThis gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CCR-1
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Beta Chemokine Rec. (CCR),SARS Coronavirus
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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