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Cinpanemab (Synonyms: BIIB054)
Catalog No. T76861 Copy Product Info
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Cinpanemab (BIIB054) is a novel human monoclonal antibody with affinity for alpha-synuclein residues 1-10. Cinpanemab can be used to study Parkinson's disease and related diseases.
Cinpanemab
Copy Product Info🥰Excellent
Catalog No. T76861
Synonyms BIIB054
Cinpanemab (BIIB054) is a novel human monoclonal antibody with affinity for alpha-synuclein residues 1-10. Cinpanemab can be used to study Parkinson's disease and related diseases.
Cinpanemab
Cas No. 2094516-02-4
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $197 | In Stock | In Stock | |
| 5 mg | $516 | In Stock | In Stock | |
| 10 mg | $828 | - | In Stock | |
| 25 mg | $1,230 | - | In Stock | |
| 50 mg | $1,650 | - | In Stock | |
| 100 mg | $2,230 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95%
Appearance:Liquid
Color:Transparent
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| Description | Cinpanemab (BIIB054) is a novel human monoclonal antibody with affinity for alpha-synuclein residues 1-10. Cinpanemab can be used to study Parkinson's disease and related diseases. |
| In vitro | Cinpanemab exhibits high selectivity for aggregated forms of α-syn, with at least an 800-fold higher apparent affinity for fibrillar recombinant α-syn compared to monomeric recombinant α-syn, and it shows a strong preference for human Parkinson's disease (PD) brain tissue[2]. |
| In vivo | Cinpanemab (30 mg/kg; intraperitoneal injection) ameliorates Parkinson's disease (PD)-like phenotypes in a mouse model inoculated with α-syn PFFs[2]. |
| Synonyms | BIIB054 |
| Reactivity | Human |
| Verified Activity | Immobilized Human Alpha-synuclein (1-140 aa, Fc) 2 μg/mL can bind Cinpanemab. The EC50 is 0.02898 μg/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Alpha-synuclein |
| Molecular Weight | 150 kDa |
| Cas No. | 2094516-02-4 |
| Isotype | Human IgG1 lambda2 |
| Recommended Isotype Control |
| Storage | -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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