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Cinpanemab
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Catalog No. T76861Cas No. 2094516-02-4
Alias BIIB054
Cinpanemab (BIIB054) is a novel human monoclonal antibody with affinity for alpha-synuclein residues 1-10. Cinpanemab can be used to study Parkinson's disease and related diseases.
Cinpanemab
Cinpanemab
😃Good
Catalog No. T76861Alias BIIB054Cas No. 2094516-02-4
Cinpanemab (BIIB054) is a novel human monoclonal antibody with affinity for alpha-synuclein residues 1-10. Cinpanemab can be used to study Parkinson's disease and related diseases.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $197 | In Stock | In Stock | |
| 5 mg | $516 | In Stock | In Stock | |
| 10 mg | $828 | - | In Stock | |
| 25 mg | $1,230 | - | In Stock | |
| 50 mg | $1,650 | - | In Stock | |
| 100 mg | $2,230 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Cinpanemab (BIIB054) is a novel human monoclonal antibody with affinity for alpha-synuclein residues 1-10. Cinpanemab can be used to study Parkinson's disease and related diseases. |
| In vitro | Cinpanemab exhibits high selectivity for aggregated forms of α-syn, with at least an 800-fold higher apparent affinity for fibrillar recombinant α-syn compared to monomeric recombinant α-syn, and it shows a strong preference for human Parkinson's disease (PD) brain tissue[2]. |
| In vivo | Cinpanemab (30 mg/kg; intraperitoneal injection) ameliorates Parkinson's disease (PD)-like phenotypes in a mouse model inoculated with α-syn PFFs[2]. |
| Synonyms | BIIB054 |
| Reactivity | Human |
| Verified Activity | Immobilized Human Alpha-synuclein (1-140 aa, Fc) 2 μg/mL can bind Cinpanemab. The EC50 is 0.02898 μg/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Alpha-synuclein |
| Molecular Weight | 150 kDa |
| Cas No. | 2094516-02-4 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 lambda2 |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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