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Dazopride [LY-237733, AHR-5531] is an antiemetic agent with the chemical composition C15H15N5O2S and a molecular weight of 329.38 g/mol. It appears as white to off-white crystalline powder, melting at 159–162°C, and is soluble in water (forceps method) and organic solvents (chlorinated solvents).

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | $1,520 | 6-8 weeks | 6-8 weeks | |
| 50 mg | $1,980 | 6-8 weeks | 6-8 weeks | |
| 100 mg | $2,500 | 6-8 weeks | 6-8 weeks |
| Description | Dazopride [LY-237733, AHR-5531] is an antiemetic agent with the chemical composition C15H15N5O2S and a molecular weight of 329.38 g/mol. It appears as white to off-white crystalline powder, melting at 159–162°C, and is soluble in water (forceps method) and organic solvents (chlorinated solvents). |
| In vivo | Dasopride (0.3 mg / kg) can significantly enhance gastric emptying. In the gastric emptying test, its efficacy is about six times higher than that of metoclopramide. Dazopril (0.3-10.0 mg / kg, intravenous) produced dose-related increases in anal motility mainly by increasing the anal contraction amplitude in three sober dogs. Dazopril significantly reduced the frequency of vomiting in the control group. Doxolipril (5 mg / kg, intraperitoneal injection) antagonizes tetralin induced vomiting, but not 0.25-2.5 mg / kg. Although larger doses of 1.0 mg / kg eliminated or weakened its response, dazopril could not change cisplatin-induced vomiting at 0.1 mg / kg (iv), while dazopride at 5.0 mg / kg antagonized vomiting in all animals development of. |
| Synonyms | AHR-5531 |
| Molecular Weight | 326.82 |
| Formula | C15H23ClN4O2 |
| Cas No. | 70181-03-2 |
| Smiles | C(NC1CN(CC)N(CC)C1)(=O)C2=C(OC)C=C(N)C(Cl)=C2 |
| Relative Density. | 1.27 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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