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Anti-Cellular Apoptosis Susceptibility Antibody (8O505)

(Synonyms: XPO2_HUMAN, XPO2, XPO 2, MGC130037, MGC130036, MGC117283, Importin-alpha re-exporter, Importin alpha re exporter, Exportin-2, Exportin2, Exportin 2, Exp2, Exp 2, CSE1L, CSE1 chromosome segregation 1 like protein, CSE1 chromosome segregation 1 like (yeast), CSE1 chromosome segregation 1 like, CSE1, CSE 1L, CSE 1 chromosome segregation 1 like protein, CSE 1 chromosome segregation 1 like, CSE 1, Chromosome segregation gene CSE1, Chromosome segregation 1-like protein, Chromosome segregation 1 like protein, Chromosome segregation 1 Like, Chromosome segregation 1 (yeast homolog) like, Cellular apoptosis susceptibility protein, CAS) Copy Product Info
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Synonyms: XPO2_HUMAN, XPO2, XPO 2, MGC130037, MGC130036, MGC117283, Importin-alpha re-exporter, Importin alpha re exporter, Exportin-2, Exportin2, Exportin 2, Exp2, Exp 2, CSE1L, CSE1 chromosome segregation 1 like protein, CSE1 chromosome segregation 1 like (yeast), CSE1 chromosome segregation 1 like, CSE1, CSE 1L, CSE 1 chromosome segregation 1 like protein, CSE 1 chromosome segregation 1 like, CSE 1, Chromosome segregation gene CSE1, Chromosome segregation 1-like protein, Chromosome segregation 1 like protein, Chromosome segregation 1 Like, Chromosome segregation 1 (yeast homolog) like, Cellular apoptosis susceptibility protein, CAS

Catalog No. TMAC-00813 Copy Product Info
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Anti-Cellular Apoptosis Susceptibility Antibody (8O505) is a Rabbit antibody targeting Cellular Apoptosis Susceptibility. Anti-Cellular Apoptosis Susceptibility Antibody (8O505) can be used in FCM,ICC,IF,IHC,WB.
Anti-Cellular Apoptosis Susceptibility Antibody
(8O505)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Cellular Apoptosis Susceptibility Antibody (8O505) is a Rabbit antibody targeting Cellular Apoptosis Susceptibility. Anti-Cellular Apoptosis Susceptibility Antibody (8O505) can be used in FCM,ICC,IF,IHC,WB.
SynonymsXPO2_HUMAN, XPO2, XPO 2, MGC130037, MGC130036, MGC117283, Importin-alpha re-exporter, Importin alpha re exporter, Exportin-2, Exportin2, Exportin 2, Exp2, Exp 2, CSE1L, CSE1 chromosome segregation 1 like protein, CSE1 chromosome segregation 1 like (yeast), CSE1 chromosome segregation 1 like, CSE1, CSE 1L, CSE 1 chromosome segregation 1 like protein, CSE 1 chromosome segregation 1 like, CSE 1, Chromosome segregation gene CSE1, Chromosome segregation 1-like protein, Chromosome segregation 1 like protein, Chromosome segregation 1 Like, Chromosome segregation 1 (yeast homolog) like, Cellular apoptosis susceptibility protein, CAS
Ig Type
IgG
Clone
8O505
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundCellular apoptosis susceptibility protein (CAS), also called Exportin 2, is a 971 amino acid member of the CSE1 family. CAS mediates Importin α re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm. In the nucleus, CAS binds cooperatively to Importin α and to the GTPase Ran in its GTP-bound (active) form. This complex binds to nucleoporins as it docks to the nuclear pore complex. Once in the cytoplasm, the complex dissociates and Importin α is released and CAS returns to the nuclear compartment and the process begins anew. CAS can be detected highly in proliferating cells. Three isoforms of CAS have been named due to alternative splicing. Isoform 1 is the full length, 971 amino acid protein. Isoform 2 contains an alternative sequence for amino acids 190-195 and is missing amino acids 196-971. Isoform 3 contains an alternative sequence for amino acids 943-945 and is missing amino acids 946-971.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 110 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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