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Anti-ROS1 Polyclonal Antibody
(Synonyms: v ros UR2 sarcoma virus oncogene homolog 1, v ros avian UR2 sarcoma virus oncogene homolog 1, Transmembrane tyrosine specific protein kinase, ROS1C, ros protein, ROS 1, ROS, Receptor tyrosine kinase c-ros oncogene 1, Proto-oncogene tyrosine-protein kinase ROS, Proto-oncogene c-Ros-1, Proto-oncogene c-Ros, Proto oncogene tyrosine protein kinase ROS precursor, Proto oncogene tyrosine protein kinase ROS, Proto oncogene c ros 1 protein, OTTHUMP00000040389, Oncogene ROS, MCF3, c-Ros receptor tyrosine kinase, c-ros, c ros1, c ros) Copy Product Info
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Synonyms: v ros UR2 sarcoma virus oncogene homolog 1, v ros avian UR2 sarcoma virus oncogene homolog 1, Transmembrane tyrosine specific protein kinase, ROS1C, ros protein, ROS 1, ROS, Receptor tyrosine kinase c-ros oncogene 1, Proto-oncogene tyrosine-protein kinase ROS, Proto-oncogene c-Ros-1, Proto-oncogene c-Ros, Proto oncogene tyrosine protein kinase ROS precursor, Proto oncogene tyrosine protein kinase ROS, Proto oncogene c ros 1 protein, OTTHUMP00000040389, Oncogene ROS, MCF3, c-Ros receptor tyrosine kinase, c-ros, c ros1, c ros
Catalog No. TMAB-01635 Copy Product Info
🥰Excellent
Anti-ROS1 Polyclonal Antibody is a Rabbit antibody targeting ROS1. Anti-ROS1 Polyclonal Antibody can be used in FCM,WB.
Anti-ROS1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Bioactivity
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| Description | Anti-ROS1 Polyclonal Antibody is a Rabbit antibody targeting ROS1. Anti-ROS1 Polyclonal Antibody can be used in FCM,WB. |
| Synonyms | v ros UR2 sarcoma virus oncogene homolog 1, v ros avian UR2 sarcoma virus oncogene homolog 1, Transmembrane tyrosine specific protein kinase, ROS1C, ros protein, ROS 1, ROS, Receptor tyrosine kinase c-ros oncogene 1, Proto-oncogene tyrosine-protein kinase ROS, Proto-oncogene c-Ros-1, Proto-oncogene c-Ros, Proto oncogene tyrosine protein kinase ROS precursor, Proto oncogene tyrosine protein kinase ROS, Proto oncogene c ros 1 protein, OTTHUMP00000040389, Oncogene ROS, MCF3, c-Ros receptor tyrosine kinase, c-ros, c ros1, c ros |
| Ig Type | IgG |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1ug/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed in brain. Expression is increased in primary gliomas. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human ROS1 |
| Antigen Species | Human |
| Gene Name | ROS1 |
| Gene ID | |
| Protein Name | Proto-oncogene tyrosine-protein kinase ROS |
| Uniprot ID | |
| Biology Area | Growth factors,Proto-oncogenes,Receptor Tyrosine Kinases |
| Function | Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2. |
| Molecular Weight | Theoretical: 258 kDa. Actual: >250/110 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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