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Paeonol

Name: Paeonol
Brand: TargetMol
SKU: T2900
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2900Cas No. 552-41-0

Alias Peonol

Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.

Paeonol

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Purity: 99.56%

Catalog No. T2900Alias PeonolCas No. 552-41-0

Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.

Pack Size	Price	Availability	Quantity
2 g	$38	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.56%

Resource Download

COA LCMS HPLC HNMR

Product Introduction

Bioactivity

Description	Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.
Targets&IC50	MAO-A:54.6 μM, MAO-B:42.5 μM
In vitro	Paeonol exhibits toxicity in mice with an LD50 range of 608-899 mg/kg when administered intraperitoneally (i.p.).
In vivo	Danpi phenol mitigates allergic reactions by modulating histamine and TNF-α (tumor necrosis factor-alpha) levels.
Synonyms	Peonol

Chemical Properties

Molecular Weight	166.17
Formula	C₉H₁₀O₃
Cas No.	552-41-0
Smiles	COC1=CC(O)=C(C=C1)C(C)=O
Relative Density.	1.158g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 33 mg/mL (198.59 mM), Sonication is recommended.

DMSO: 252 mg/mL (1516.52 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	6.0179 mL	30.0897 mL	60.1793 mL	300.8967 mL
5 mM	1.2036 mL	6.0179 mL	12.0359 mL	60.1793 mL
10 mM	0.6018 mL	3.0090 mL	6.0179 mL	30.0897 mL
20 mM	0.3009 mL	1.5045 mL	3.0090 mL	15.0448 mL
50 mM	0.1204 mL	0.6018 mL	1.2036 mL	6.0179 mL
100 mM	0.0602 mL	0.3009 mL	0.6018 mL	3.0090 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc