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Anti-IGFBP-6 Antibody-HRP (8H341)

🥰Excellent
Catalog No. TMAY-02438H

Anti-IGFBP-6 Antibody-HRP (8H341) is a HRP-conjugated Rabbit antibody targeting IGFBP-6. Anti-IGFBP-6 Antibody-HRP (8H341) can be used in ELISA.

Anti-IGFBP-6 Antibody-HRP (8H341)

Anti-IGFBP-6 Antibody-HRP (8H341)

🥰Excellent
Catalog No. TMAY-02438H
Anti-IGFBP-6 Antibody-HRP (8H341) is a HRP-conjugated Rabbit antibody targeting IGFBP-6. Anti-IGFBP-6 Antibody-HRP (8H341) can be used in ELISA.
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Product Introduction

Bioactivity
Description
Anti-IGFBP-6 Antibody-HRP (8H341) is a HRP-conjugated Rabbit antibody targeting IGFBP-6. Anti-IGFBP-6 Antibody-HRP (8H341) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
Clone
8H341
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 0.1-1 μg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human IGFBP6 / IBP6 (rh IGFBP6 / IBP6; TMPY-02119; P24592; Met1-Gly240), and conjugated with horseradish-peroxidase (HRP).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundInsulin-like growth factor-binding protein 6 (IGFBP6) is a 24-kDa protein that binds insulin-like growth factor 1 (IGF-1) and IGF-2 with high affinity and inhibits IGF action in vitro. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF or act in an IGF-independent manner in the prostate. IGF-binding protein-4 (IGFBP-4) inhibits IGF-I action in vitro and is the most abundant IGFBP in the rodent arterial wall. IGFBP6 is directly downregulated by the beta-catenin/TCF complex in desmoid tumors, and imply a role for the IGF axis in the proliferation of desmoid tumors. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence, and IGF affinity.
Related Conjugates and Formulations
Conjucates
HRP
Others Formats
Unconjugated
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Human IGFBP6 / IBP6 Protein (TMPY-02119)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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