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Anti-SENP1 Antibody (9W647)

(Synonyms: Sentrin-specific protease 1, Sentrin/SUMO-specific protease SENP1, SENP 1) Copy Product Info
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Synonyms: Sentrin-specific protease 1, Sentrin/SUMO-specific protease SENP1, SENP 1

Catalog No. TMAH-01084 Copy Product Info
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Anti-SENP1 Antibody (9W647) is an antibody targeting SENP1. Anti-SENP1 Antibody (9W647) can be used in ELISA,FCM,IF,IHC,WB.
Anti-SENP1 Antibody
(9W647)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2087-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SENP1 Antibody (9W647) is an antibody targeting SENP1. Anti-SENP1 Antibody (9W647) can be used in ELISA,FCM,IF,IHC,WB.
SynonymsSentrin-specific protease 1, Sentrin/SUMO-specific protease SENP1, SENP 1
Ig Type
Rabbit IgG
Clone
9W647
Reactivity
Human
Application
Recommended Dose
WB:1:500-1:2000; IHC:1:50-1:200; IF:1:50-1:200; FCM:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationNucleus. Cytoplasm. Note=Shuttles between cytoplasm and nucleus.
Tissue SpecificityHighly expressed in testis. Expressed at lower levels in thymus, pancreas, spleen, liver, ovary and small intestine.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundProtease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1. Deconjugates SUMO1 from METTL3. Desumoylates CCAR2 which decreases its interaction with SIRT1. Deconjugates SUMO1 from GPS2.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human SENP1
Antigen Species
Human
Gene Name
SENP1
Gene ID
Uniprot ID
Biology Area
Epigenetics and Nuclear Signaling, Cell biology
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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