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4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide

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Catalog No. T66390Cas No. 757251-39-1

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide is an aromatic enigma that is is a metabolite of the antitumor drug rafenil.

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide

🥰Excellent
Purity: 98.38%
Catalog No. T66390Cas No. 757251-39-1
4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide is an aromatic enigma that is is a metabolite of the antitumor drug rafenil.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$30-In Stock
25 mg$46-In Stock
50 mg$67-In Stock
100 mg$100-In Stock
500 mg$245-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.38%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide is an aromatic enigma that is is a metabolite of the antitumor drug rafenil.
Chemical Properties
Molecular Weight261.25
FormulaC13H12FN3O2
Cas No.757251-39-1
SmilesCNC(=O)c1cc(Oc2ccc(N)c(F)c2)ccn1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (191.39 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.8278 mL19.1388 mL38.2775 mL191.3876 mL
5 mM0.7656 mL3.8278 mL7.6555 mL38.2775 mL
10 mM0.3828 mL1.9139 mL3.8278 mL19.1388 mL
20 mM0.1914 mL0.9569 mL1.9139 mL9.5694 mL
50 mM0.0766 mL0.3828 mL0.7656 mL3.8278 mL
100 mM0.0383 mL0.1914 mL0.3828 mL1.9139 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

DrugMetaboliteDrug Metabolite
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