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4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide

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Catalog No. T66390Cas No. 757251-39-1

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide is an aromatic enigma that is is a metabolite of the antitumor drug rafenil.

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide

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Purity: 98.38%
Catalog No. T66390Cas No. 757251-39-1
4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide is an aromatic enigma that is is a metabolite of the antitumor drug rafenil.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$30-In Stock
25 mg$46-In Stock
50 mg$67-In Stock
100 mg$100-In Stock
500 mg$245-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.38%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide is an aromatic enigma that is is a metabolite of the antitumor drug rafenil.
Chemical Properties
Molecular Weight261.25
FormulaC13H12FN3O2
Cas No.757251-39-1
SmilesCNC(=O)c1cc(Oc2ccc(N)c(F)c2)ccn1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (191.39 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.8278 mL19.1388 mL38.2775 mL191.3876 mL
5 mM0.7656 mL3.8278 mL7.6555 mL38.2775 mL
10 mM0.3828 mL1.9139 mL3.8278 mL19.1388 mL
20 mM0.1914 mL0.9569 mL1.9139 mL9.5694 mL
50 mM0.0766 mL0.3828 mL0.7656 mL3.8278 mL
100 mM0.0383 mL0.1914 mL0.3828 mL1.9139 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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