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PPIL2 Protein, Human, Recombinant (aa 280-457, His)

Catalog No. TMPY-03413
Synonyms: UBOX7, Cyp-60, CYP60, CYC4, peptidylprolyl isomerase (cyclophilin)-like 2, hCyP-60

PPIL2, is an enzyme that belongs to the cyclophilin family. The cyclophilins are peptidylprolyl isomerases and are highly conserved ubiquitous. They play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL2 interacts with the proteinase inhibitor eglin c and is localized in the nucleus. It contains 1 PPIL2 cyclophilin-type domain and 1 U-box domain. PPIL2 accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

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PPIL2 Protein, Human, Recombinant (aa 280-457, His)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 700.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description PPIL2, is an enzyme that belongs to the cyclophilin family. The cyclophilins are peptidylprolyl isomerases and are highly conserved ubiquitous. They play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL2 interacts with the proteinase inhibitor eglin c and is localized in the nucleus. It contains 1 PPIL2 cyclophilin-type domain and 1 U-box domain. PPIL2 accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Species Human
Expression System E. coli
Tag His
Accession Number Q13356-2
Synonyms UBOX7, Cyp-60, CYP60, CYC4, peptidylprolyl isomerase (cyclophilin)-like 2, hCyP-60
Construction A DNA sequence encoding the mature form of human PPIL2 (Q13356-2) (Gly280-Pro457) was expressed with a polyhistide tag at the N-terminus.
Protein Purity > 95 % as determined by SDS-PAGE
Molecular Weight Approxiamtely 21.9 kDa
Endotoxin Please contact us for more information.
Formulation Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background PPIL2, is an enzyme that belongs to the cyclophilin family. The cyclophilins are peptidylprolyl isomerases and are highly conserved ubiquitous. They play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL2 interacts with the proteinase inhibitor eglin c and is localized in the nucleus. It contains 1 PPIL2 cyclophilin-type domain and 1 U-box domain. PPIL2 accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

References and Literature

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Keywords

PPIL2 Protein, Human, Recombinant (aa 280-457, His) UBOX7 UBOX-7 Cyp-60 CYP60 CYC4 UBOX 7 peptidylprolyl isomerase (cyclophilin)-like 2 CYC-4 CYP 60 CYC 4 hCyP-60 recombinant recombinant-proteins proteins protein

 

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