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Anti-Phospho-PLCγ1 (Tyr1253) Polyclonal Antibody

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Catalog No. TMAC-03368

Anti-Phospho-PLCγ1 (Tyr1253) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCγ1 (Tyr1253). Anti-Phospho-PLCγ1 (Tyr1253) Polyclonal Antibody can be used in WB,ELISA.

Anti-Phospho-PLCγ1 (Tyr1253) Polyclonal Antibody

Anti-Phospho-PLCγ1 (Tyr1253) Polyclonal Antibody

😃Good
Catalog No. TMAC-03368
Anti-Phospho-PLCγ1 (Tyr1253) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCγ1 (Tyr1253). Anti-Phospho-PLCγ1 (Tyr1253) Polyclonal Antibody can be used in WB,ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$2187-10 days
100 μL$3187-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-PLCγ1 (Tyr1253) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCγ1 (Tyr1253). Anti-Phospho-PLCγ1 (Tyr1253) Polyclonal Antibody can be used in WB,ELISA.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; ELISA: 1:20000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research Backgroundphospholipase C gamma 1(PLCG1) Homo sapiens The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human PLCG1 around the phosphorylation site of Tyr1253. AA range:1221-1270
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 150 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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