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CX3CL1/Fractalkine Protein, Human, Recombinant (S199N, CHO)
(Synonyms: SCYD1, NTT, NTN, neurotactin, fractalkine, CXC3C, CXC3, CX3CL1, C-X3-C motif chemokine ligand 1, C3Xkine, ABCD-3) Copy Product InfoSynonyms: SCYD1, NTT, NTN, neurotactin, fractalkine, CXC3C, CXC3, CX3CL1, C-X3-C motif chemokine ligand 1, C3Xkine, ABCD-3
Catalog No. TMPS-00036 Copy Product Info
CX3CL1/Fractalkine Protein, Human, Recombinant (S199N, CHO) is expressed in CHO Cells. The accession number is P78423.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $113 | 7-10 days | 7-10 days | |
| 10 µg | $143 | 7-10 days | 7-10 days | |
| 25 µg | $198 | 7-10 days | 7-10 days | |
| 50 µg | $326 | 7-10 days | 7-10 days | |
| 100 µg | $538 | 7-10 days | 7-10 days | |
| 200 µg | $898 | 7-10 days | 7-10 days | |
| 500 µg | $1,770 | 7-10 days | 7-10 days | |
| 1 mg | $2,970 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | The EC 50 value of Human Fractalkine/CX3CL1 on Ca 2+ mobilization assay in CHO-K1/Gα15/hCX3CR1 cells (human Gα15 and hCX3CR1 stably expressed in CHO-K1 cells) is less than 1.5 μg/ml. |
| Description | CX3CL1/Fractalkine Protein, Human, Recombinant (S199N, CHO) is expressed in CHO Cells. The accession number is P78423. |
| Species | Human |
| Expression System | CHO Cells |
| Tag | Tag Free |
| Accession Number | P78423 |
| Construction | Gln25-Arg339 (Ser199Asn) |
| Protein Purity | > 95% as determined by SDS-PAGE |
| Endotoxin | < 0.2 EU/μg of protein as determined by the LAL method. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | SCYD1, NTT, NTN, neurotactin, fractalkine, CXC3C, CXC3, CX3CL1, C-X3-C motif chemokine ligand 1, C3Xkine, ABCD-3 |
| Research Background | Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a known member of the CX3C chemokine family. It is also commonly known under the names fractalkine (in humans) and neurotactin (in mice). The polypeptide structure of CXC3L1 differs from the typical structure of other chemokines. For example, the spacing of the characteristic N-terminal cysteines is different; there are three amino acids separating the initial pair of cysteines in CX3CL1, while there are none in CC chemokines and only one in CXC chemokines. CX3CL1 is produced as a long protein (with 373-amino acid in humans) with an extended mucin-like stalk and a chemokine domain on top. The mucin-like stalk allows it to bind to the surface of certain cells. Soluble CX3CL1 potently chemoattracts T cells and monocytes, while the cell-bound chemokine promotes strong adhesion of leukocytes to activated endothelial cells, where it is primarily expressed. CX3CL1 can signal through the chemokine receptor CX3CR1. |
| Molecular Weight | 50~75 kDa (Reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
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Related Tags: CX3CL1/Fractalkine Protein, Human, Recombinant (S199N, CHO) chemical structure | CX3CL1/Fractalkine Protein, Human, Recombinant (S199N, CHO) molecular weight
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