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ASGR1 Protein, Rat, Recombinant (His & Myc)

Catalog No. TMPH-03248
Synonyms: Asialoglycoprotein receptor 1, ASGP-R 1, rHL-1, Asgr1, HL-1, Asgr-1, Hepatic lectin 1, ASGPR 1

Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.

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ASGR1 Protein, Rat, Recombinant (His & Myc)
Pack Size Availability Price/USD Quantity
20 μg 20 days $ 614.00
100 μg 20 days $ 1,720.00
1 mg 20 days $ 7,240.00
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Biological Description
Technical Params
Product Properties
Description Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Species Rat
Expression System HEK293
Tag N-terminal 10xHis-tagged and C-terminal Myc-tagged
Accession Number P02706
Synonyms Asialoglycoprotein receptor 1, ASGP-R 1, rHL-1, Asgr1, HL-1, Asgr-1, Hepatic lectin 1, ASGPR 1
Amino Acid QNSQLREDLRVLRQNFSNFTVSTEDQVKALTTQGERVGRKMKLVESQLEKHQEDLREDHSRLLLHVKQLVSDVRSLSCQMAALRGNGSERICCPINWVEYEGSCYWFSSSVKPWTEADKYCQLENAHLVVVTSWEEQRFVQQHMGPLNTWIGLTDQNGPWKWVDGTDYETGFKNWRPGQPDDWYGHGLGGGEDCAHFTTDGHWNDDVCRRPYRWVCETELGKAN Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Construction 61-284 aa
Protein Purity > 90% as determined by SDS-PAGE.
Molecular Weight 31 kDa (predicted)
Formulation If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.

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Keywords

ASGR1 Protein, Rat, Recombinant (His & Myc) Asialoglycoprotein receptor 1 ASGP-R 1 rHL-1 Asgr1 HL-1 Asgr-1 Hepatic lectin 1 ASGPR 1 recombinant recombinant-proteins proteins protein

 

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