Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DA-PROTAC is a potent degrader of the copper ion-transport proteins Atox1 and CCS, capable of binding to both proteins and facilitating their association with E3 ligase. This interaction enhances the ubiquitination and subsequent proteasomal degradation of Atox1 and CCS. DA-PROTAC is utilized in triple negative breast cancer research [1].
Pack Size | Availability | Price/USD | Quantity |
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5 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | DA-PROTAC is a potent degrader of the copper ion-transport proteins Atox1 and CCS, capable of binding to both proteins and facilitating their association with E3 ligase. This interaction enhances the ubiquitination and subsequent proteasomal degradation of Atox1 and CCS. DA-PROTAC is utilized in triple negative breast cancer research [1]. |
In vitro | DA-PROTAC (0-1$, 24 h) induces the degradation of Atox1 and CCS proteins without inhibiting their activity [1]. |
Molecular Weight | 1010.96 |
Formula | C46H50BrF2N7O8S2 |
CAS No. | 2488660-12-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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DA-PROTAC 2488660-12-2 PROTAC PROTACs inhibitor inhibit