Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-PPM1A Antibody (9J908)
😃Good
Catalog No. TMAY-02429
Alias protein phosphatase, Mg2+/Mn2+ dependent, 1A, PP2C-α, PP2Cα, PP2C-ALPHA, PP2Calpha, PP2CA
Anti-PPM1A Antibody (9J908) is a Mouse antibody targeting PPM1A. Anti-PPM1A Antibody (9J908) can be used in ELISA.
Anti-PPM1A Antibody (9J908)
Anti-PPM1A Antibody (9J908)
😃Good
Catalog No. TMAY-02429Alias protein phosphatase, Mg2+/Mn2+ dependent, 1A, PP2C-α, PP2Cα, PP2C-ALPHA, PP2Calpha, PP2CA
Anti-PPM1A Antibody (9J908) is a Mouse antibody targeting PPM1A. Anti-PPM1A Antibody (9J908) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-PPM1A Antibody (9J908) is a Mouse antibody targeting PPM1A. Anti-PPM1A Antibody (9J908) can be used in ELISA. |
| Alias | protein phosphatase, Mg2+/Mn2+ dependent, 1A, PP2C-α, PP2Cα, PP2C-ALPHA, PP2Calpha, PP2CA |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 9J908 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PPM1A / PP2C-alpha (rh PPM1A / PP2C-alpha; TMPY-02567; P35813-1; Met 1-Trp 382). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Protein phosphatase 1A (PPM1A / PP2CA) is an enzyme belonging to the PP2C family of Ser / Thr protein phosphatases. Members of PP2C family are negative regulators of cell stress response pathways and the MAP kinases and MAP kinase kinases. It has also been demonstrated to inhibit the activation of p38 and JNK kinase cascades. PPM1A dephosphorylates and promotes nuclear export of TGFβ-activated Smad2/3. Ectopic expression of PPM1A abolishes TGFβ-induced antiproliferative and transcriptional responses, whereas depletion of PPM1A enhances TGFβ signaling in mammalian cells. It has been demonstrated that PPM1A / PP2CA, through dephosphorylation of Smad2/3, plays a critical role in terminating TGFβ signaling. Overexpression of PPM1A is reported to activate the expression of the tumor suppressor gene TP53 / p53, which leads to cell apoptosis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human PPM1A / PP2C-alpha protein (TMPY-02567) |
| Antigen Species | Human |
| Biology Area | Phosphatases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-PPM1A Antibody (9J908) | purchase Anti-PPM1A Antibody (9J908) | Anti-PPM1A Antibody (9J908) cost | order Anti-PPM1A Antibody (9J908)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.