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Anti-Peroxiredoxin 6 Antibody (6V183) (Synonyms: PRX, peroxiredoxin 6, p29, NSGPx, HEL-S-128m, AOP2, aiPLA...)
Catalog No. TMAC-03416 Copy Product Info
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Anti-Peroxiredoxin 6 Antibody (6V183) is a Rabbit antibody targeting Peroxiredoxin 6. Anti-Peroxiredoxin 6 Antibody (6V183) can be used in ICC/IF,IP,WB.
Anti-Peroxiredoxin 6 Antibody (6V183)
Copy Product Info🥰Excellent
Catalog No. TMAC-03416
Synonyms PRX, peroxiredoxin 6, p29, NSGPx, HEL-S-128m, AOP2, aiPLA2, 1-Cys
Anti-Peroxiredoxin 6 Antibody (6V183) is a Rabbit antibody targeting Peroxiredoxin 6. Anti-Peroxiredoxin 6 Antibody (6V183) can be used in ICC/IF,IP,WB.
Anti-Peroxiredoxin 6 Antibody
(6V183)
(6V183)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Peroxiredoxin 6 Antibody (6V183) is a Rabbit antibody targeting Peroxiredoxin 6. Anti-Peroxiredoxin 6 Antibody (6V183) can be used in ICC/IF,IP,WB. |
| Synonyms | PRX, peroxiredoxin 6, p29, NSGPx, HEL-S-128m, AOP2, aiPLA2, 1-Cys |
| Ig Type | IgG |
| Clone | 6V183 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of PRDX6 on Jurkat cells lysates using anti-PRDX6 antibody at 1/500 dilution. Positive control: Line 1: Hela, Line 2:HepG2.  |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:10-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metal-catalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, although they are fairly promiscuous with regard to the hydroperoxide substrate. In addition to protection from ROS, peroxiredoxins are also involved in cell proliferation, differentiation and gene expression. PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization. The human PRX I gene encodes a protein that is expressed in several tissues, including liver, kidney, testis, lung and nervous system. PRX II is expressed in testis, while PRX III shows expression in lung. PRX I, II and III are overexpressed in breast cancer and may be involved in its development or progression. Upregulated protein levels of PRX I and II in Alzheimer's disease (AD) and Down syndrome (DS) indicate the involvement of PRX I and II in their pathogenesis. The human PRX IV gene is abundantly expressed in many tissues. PRX IV exists as a precursor protein, which is only detected in testis, and a processed secreted form. PRX V also exists as two forms, designated long and short. Like PRX IV, the long form of PRX V is highly expressed in testis. The short form of PRX V is more widely expressed, with high expression in liver, kidney, heart and lung. PRX VI, a 1-Cys peroxiredoxin (also known as antioxidant protein 2 or AOP2), is highly expressed in most tissues, particularly in epithelial cells. Localized to the cell cytosol, PRX VI functions independently of other peroxiredoxins and antioxidant proteins, specializing in antioxidant defense, lung phospholipid metabolism and protection of keratinocytes from cell death induced by reactive oxygen species. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 25 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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