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Anti-ULBP-2 Antibody (4Z93)
🥰Excellent
Catalog No. TMAY-02253
Anti-ULBP-2 Antibody (4Z93) is a Rabbit antibody targeting ULBP-2. Anti-ULBP-2 Antibody (4Z93) can be used in IHC-P.
Anti-ULBP-2 Antibody (4Z93)
Anti-ULBP-2 Antibody (4Z93)
🥰Excellent
Catalog No. TMAY-02253
Anti-ULBP-2 Antibody (4Z93) is a Rabbit antibody targeting ULBP-2. Anti-ULBP-2 Antibody (4Z93) can be used in IHC-P.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-ULBP-2 Antibody (4Z93) is a Rabbit antibody targeting ULBP-2. Anti-ULBP-2 Antibody (4Z93) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4Z93 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human ULBP2 in human renal carcinoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human ULBP2 in human hepatoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of human ULBP2 in human gastric cancer with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ULBP2 / N2DL-2 (rh ULBP2 / N2DL-2; TMPY-02333; Q9BZM5; Met1-Ser217). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human ULBP2 / N2DL-2 protein (TMPY-02333) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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