Claudin-9 Protein, Human, Recombinant

Name: Claudin-9 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-06902
Rating: 4.5 (1 reviews)

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Catalog No. TMPY-06902 Copy Product Info

Claudin-9 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 22.9 kDa and the accession number is O95484.

Pack Size	Price	USA Stock	Global Stock
10 µg	$597	7-10 days	7-10 days
20 µg	$1,000	7-10 days	7-10 days
50 µg	$1,530	7-10 days	7-10 days
100 µg	$2,430	7-10 days	7-10 days
200 µg	$3,630	7-10 days	7-10 days
500 µg	$8,630	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human CLDN9-VLP (Full Length) Protein at 5 μg/mL (100 μL/well) can bind Anti-Human CLDN9 Antibody,Human IgG1, the EC50 is 1-10 ng/mL.
Description	Claudin-9 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 22.9 kDa and the accession number is O95484.
Species	Human
Expression System	HEK293 Cells
Tag	Tag Free
Accession Number	O95484
Construction	A DNA sequence encoding the human CLDN9 (O95484) (Met1-Val217) was expressed. Predicted N terminal: Met 1
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as sterile 50 mM Hepes, 150 mM NaCl, 10% Trehalose, pH 7.2.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Research Background	Claudin-9 (CLDN9) belongs to the claudins family and is a transmembrane protein found in tight junctions with two extracellular loops and a cytoplasmic C tail. CLDN9 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It forms heterotypic interactions with other claudins to create cation-selective channels in the kidney and may contribute to the maintenance of alveolar barrier function in the lung. Deficiency is shown to be associated with autosomal recessive deafness, DFNB116. CLDN9 expression has been shown to be upregulated in certain types of cancer, such as endometrial cancer and hepatocellular carcinoma, and its knockdown has been found to reduce cell proliferation and migration in vitro.

Chemical Properties

Molecular Weight

22.9 kDa (predicted)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.